Palacios-Cruz L, Arias-Caballero A, Cortés SF, de la Peña-Olvera F, Feria AM, Cárdenas GM, Apiquian-Guitart R, Cabrera-Lagunes A, Berlanga C, Fresán A, Heinze-Martin G

Language: Spanish
References: 32
Page: 241-251
PDF size: 348.53 Kb.

ABSTRACT

Background: Early onset mania (MIMT), compared with adolescent onset mania (MIA), has a different clinical presentation of classic mania adult onset (MIEA). Patients with MIA have a course more like the MIEA. Externalizing disorders (ADHD, ODD, and TC) have been associated with an earlier age of onset of bipolar disorder and as a marker of poor prognosis. Our goal is to determine the frequency of symptoms related to disruptive behavior disorders in patients with bipolar disorder start very early, early and adult evaluated retrospectively.
Methods: The total sample (N=64) of adolescent and adult patients was obtained from the National Institute of Psychiatry (INPRF) clinics. The diagnosis was confirmed by the research team. Patients signed the informed asentment and consentment. We applied the K SADS PL Mexico, MINI and MINI KID. We used the EEPE-AA for externalizing disorders.
Results: There were significant differences in scores compared by EEPE AA EIED groups in the Inattention subscale for GIMT. The presence of ADHD, ODD, TC and Suicide Risk in the time of evaluation was significantly associated with an earlier onset.
Discussion and conclusion: Our data supports the clinical utility and importance of separating the TBP by age of onset. The detection of externalizing disorders may speak of an early onset of the disorder and may also have implications for prognosis and psychopharmacological treatment, since the TBPonset childhood to adulthood remains similar and difficult to manage. This suggests that we must have a longitudinal view of this disorder.

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