Gallegos-Arzola R, Rojas-Saiz WH, Rocha MG, Carrero-Soto H, Rendón MME

Language: Spanish
References: 13
Page: 69-75
PDF size: 383.22 Kb.

ABSTRACT

Inflammation post-intubation is a frequent phenomenon. The use of orotraqueal balloon at controlled pressures allows reducing this complication. But, the time effect still needs to be evaluated or still needs evaluation. Objective: To evaluate the inflammatory cellular reaction (by Papanicolaou method) in patient with different times of intubation. Material and methods: We recruited 64 patients (18 to 90 years old), with no-urgent surgery, ASA 1-2, with clinically easy intubation and pre-medication with AINES or steroids. During the intubation, the balloon pressure was maintaining ‹ 20 mmHg. At take out the orotraqueal cannula, a cytology smear was obtained. The level of inflammation was assessed by one cytopathologic observer (intra-rater Kappa = 0.97), as absent, medium, moderate or severity. Results: All patients showed some inflammatory reaction. All those with less than 75 minutes of intubation showed medium inflammation (9), in those between 75 to 120 minutes predominated middle inflammation over moderate (14 versus 11), and in those with more than 120 minutes predominated a moderate inflammation (19 versus 11), χ² lineal by lineal 8.8_1fg p = 0.003. In multivariable adjustment, per each 30 minutes the risk of moderate inflammation increased 1.6 (CI_95%; 1.08-2.4, p = 0.02). There were not patient with severity inflammation. Conclusions: The time of orotraqueal intubation increase the risk of cellular inflammation reaction eventhough pressure is adequate.

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