2013, Number 3
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Gac Med Mex 2013; 149 (3)
In vitro assessment of UVA protection by sunscreens for prescription in Mexico
Castanedo CJP, Torres ÁB, Valdés GG, Ehnis PA
Language: Spanish
References: 22
Page: 292-298
PDF size: 91.70 Kb.
ABSTRACT
An appropriate sunscreen should provide a high and broad ultraviolet (UV) protection for both UVB (290-329 nm) and UVA (329-400 nm) segments.
Objective: to quantify the UVA protection in vitro of 68 sunscreens available for medical prescription in Mexico.
Methods: UV absorbance was quantified through two simple and easy to interpret methods: the critical length of absorption (Cλ), and spectral uniformity index (SUI).
Results: based on the Cλ, 97% of the products absorbed 90% or more of the radiation between 290-370 nm. The SUI showed that 41% (n = 28) offer high protection, and 35% very high (n = 34). We did not find an association between the sun protecting factor (SPF) and Cλ.
Conclusion: in contrast to previous sunscreens, recent ones show a noticeable improvement in UVA absorption. Because SPF refers to only UVB protection, the prescription of these products should not be established only by this value, but by its capacity to have broad UV coverage. The most common active ingredients found in the sunscreens with better UVA protection were titanium dioxide, avobenzone, bemotrizinol and bisoctrizole.
REFERENCES
Castanedo-Cázares JP, Lepe V, Gordillo-Moscoso A, Moncada B. Ultraviolet radiation doses in Mexican students. Salud Pública Mex. 2003; 45:439-44.
Castanedo Cázares JP, Torres Álvarez B, Sobrevilla Ondarza S, Ehnis Pérez A, Gordillo Moscoso A. Estimación del tiempo de exposición solar para quemadura en población mexicana. Gac Med Mex. 2012; 148:243-7.
Koh HK, Geller AC, Miller DR, Grossbart TA, Lew RA. Prevention and early detection strategies for melanoma and skin cancer. Arch Dermatol. 1996;132:436-43.
Wikonkai NM, Brash DE. Ultraviolet radiation induced signature mutations in photocarcinogenesis. J Invest Dermatol Symp Proc. 1999;46-9.
Yaar M, Gilchrest BA. Aging and photoaging: postulated mechanisms and effectors. J Invest Dermatol Symp Proc. 1998;3:47-51.
Nishigori C, Yarosh DB, Donawho C, Kripke ML. The immune system in ultraviolet carcinogenesis. J Invest Dermatol Symp Proc. 1996;1:143-6.
Sliney DH. Epidemiological studies of sunlight and cataract: the critical factor of ultraviolet exposure geometry. Ophthalmic Epidemiol. 1994;1: 107-19.
Serre I, Cano JP, Picot MC, Meynadier J, Meunier L. Immunosuppression induced by acute solar-simulated ultraviolet exposure in humans: prevention by a sunscreen with a sun protection factor of 15 and high UVA protection. J Am Acad Dermatol. 1997;37:187-94.
Krutmann J. Ultraviolet A radiation-induced biological effects in human skin: relevance for photoaging and photodermatosis. J Dermatol Sci. 2000;23 Suppl 1:22-6.
Lowe NJ. An overview of ultraviolet radiation, sunscreens, and photoinduced dermatoses. Dermatol Clin. 2006;24:9-17.
Department of Health and Human Services FDA, USA. Sunscreen drug products for over the counter use: proposed amendment of final monograph; proposed rule. Federal Register. 2007;72:49070-122.
Castanedo-Cázares JP, Torres-Álvarez B, Briones-Estevis S, Moncada B. La inconsistencia del factor de protección solar (FPS) en México. El caso de los filtros para piel oleosa. Gac Med Mex. 2005;141:111-4.
Castanedo-Cázares JP, Torres-Álvarez B, Araujo-Andrade C, Castanedo-Tardan MP, Moncada B. Absorción ultravioleta de los protectores solares para prescripción en México. Gac Med Mex. 2008;144:35-8.
Norma Oficial Mexicana. NOM-141-SSA1-1995. Bienes y servicios. Etiquetado para productos de perfumería y belleza preenvasados. Secretaría de Salud, México.
Reglamento de control sanitario de productos y servicios. Diario Oficial de la Federación, 9 de agosto de 1999. Gobierno Federal, México.
Carrasco A, ed. Diccionario de especialidades farmacéuticas (DEF). 57.a ed. México, D.F.: Thomson PLM; 2011.
Akrman J, Kubác L, Bendová H, Jírová D, Kejlová K. Quartz plates for determining sun protection in vitro and testing photostability of commercial sunscreens. Int J Cosmet Sci. 2009;31:119-29.
Diffey BL, Tanner PR, Matts PJ, Nash JF. In vitro assessment of the broad-spectrum ultraviolet protection of sunscreen products. J Am Acad Dermatol. 2000;43:1024-35.
Diffey B. Spectral uniformity: a new index of broad spectrum (UVA) protection. Int J Cosmet Sci. 2009;31:63-8.
Kullavanijaya P, Lim HW. Photoprotection. J Am Acad Dermatol. 2005;52:937-58.
Castanedo-Cázares JP, Torres-Álvarez B, Medellín-Pérez ME, Aguilar-Hernandez GA, Moncada B. Conocimientos y actitudes de la población mexicana con respecto a la radiación solar. Gac Med Mex. 2006;142:451-5.
Diffey BL. When should sunscreen be reapplied? J Am Acad Dermatol. 2001;45:882-5.