2011, Number 3
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Rev Hosp Jua Mex 2011; 78 (3)
Modificación del volumen macular por engrosamiento del área temporal, en edema macular diabético focal
Razo-Blanco HDM, Vargas-Romero DM, Bermúdez-Zapata DA, Lima-Gómez V
Language: Spanish
References: 27
Page: 146-151
PDF size: 170.53 Kb.
ABSTRACT
Background. Eyes with diabetic macular edema without thickening in the temporal sector of the macula, improve their vision more
frequently after photocoagulation; a larger volume reduction or a larger visual deficiency before treatment could be associated
with a larger functional change, but it is unknown whether these variables differ significantly between eyes with and without
thickening in the temporal sector of the macula.
Material and methods. Non-interventional, comparative, retrospective, crosssectional
study. Patients with focal diabetic macular edema who had an optical coherence tomography fast macular map before
photocoagulation were included; eyes were assigned to one of two groups: 1 (with thickening in field 7, external temporal sector
of the macula) or 2 (without it). The means of best corrected visual acuity and macular volume (Student’s t) and the proportions of
best corrected visual acuity ‹ 0.5 and thickening of the center point (χ
2, odds ratio [OR]) were compared between groups.
Results.
90 eyes, 62.2% from females; mean age 60.31 years. The proportion of best corrected visual acuity ‹ 0.5 and the mean of best
corrected visual acuity did not differ between groups; the proportion of eyes with thickening of the center point was higher in
group 1 (p = 0.001); mean macular volume in group 1 (8.31 mm
3) was significantly higher than in group 2 (7.31 mm
3, p ‹ 0.001).
Conclusions. Macular volume was lower in eyes without thickening of field 7. Evaluation of therapies for diabetic macular edema,
should consider this difference, in order to prevent bias when efficacy is estimated.
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