2013, Number 3
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Acta Pediatr Mex 2013; 34 (3)
Pertussis: clinical and bacteriological diagnosis of six cases
Arellano-Penagos M, Aranda-Patrón E, López-Sotomayor LL
Language: Spanish
References: 40
Page: 127-131
PDF size: 192.12 Kb.
ABSTRACT
Pertussis is an endemic disease in our population. Every 3 to 4
years, pertussis has an epidemic pattern even in countries with
good health conditions. Antipertussis vaccine first dose is administered
at the age of 2 months; a second and third dose are given at
4 and 6 months of age. This vaccine has an 8 to 10 year protective
effect, for which reason it is suggested that pregnant women in the
third trimester should be vaccinated in order to prevent pertussis in
newborns. It should also be administered to older people to avoid
turning them into asymptomatic carriers. Clinic manifestations are
easily identifiable due to respiratory symptoms, especially to the
particular characteristics of the cough.
The diagnosis is supported by the presence of leukocytosis
(predominantly lymphocytes) and by certain thoracic radiologic
findings. The diagnosis is confirmed with a positive culture for
Bordetella pertussis or with a polymerase chain reaction (PCR).
In a non complicated clinic course macrolides are still the best
therapeutic choice. Nonetheless clinic observation is highly recommended
in order to avoid complications. Redefinition of vaccine
programs against Bordetella pertussis in Mexican population is
recommended and also to notify the presence of the disease to
the corresponding health authorities.
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