2011, Number 1
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Rev Invest Clin 2011; 63 (1)
Laser ablation of the placental vascular anastomoses for the treatment of twin-to-twin transfusion syndrome
Hernández-Andrade E, Guzmán-Huerta M, Benavides-Serralde JA, Páez-Serralde F, Camargo-Marín L, Acevedo-Gallegos S, Moreno-Álvarez Ó, Mancilla-Ramírez J
Language: Spanish
References: 21
Page: 46-52
PDF size: 126.78 Kb.
ABSTRACT
Aim. To report the experience of the intrauterine treatment
of monochorionic biamnotic (MC/BA) twin pregnancies complicated
with twin-to-twin transfusion syndrome (TTTS)
applying laser ablation of the placental vascular anastomoses
(LAPVA).
Material and methods. During 18 months period
35 MC/BA twin pregnancies were treated. TTTS was
diagnosed based on the discrepancies in amniotic fluid and
bladder size between both twins. Severity of TTTS was classified
according to the hemodynamic changes in both twins.
LAPVA was performed between 16-26 weeks of gestation
using a rigid straight fetoscope and a YAG (neodymium:
yttrium aluminium garnet) laser equipment. Survival was
considered when the neonate was home discharged.
Results.
Overall survival was 62.8% (44/70 fetuses). In 77% of pregnancies
(27/35) at least one twin survived, and in 48.5% (17/
35) of cases both twins survived. Bleed was the most frequent
complication (12/35; 34%). In 5 cases there was severe bleeding
leading to late premature rupture of membranes and
death of both twins. Median time stay in the neonatal intensive
care unit was 20 days (range, 7-120). There were no signs
of brain damage at the time of discharge.
Conclusion. These
results are similar to those already published. Bleeding was
the most frequent complication, however as the experience improved
it was less frequent. Overall success is highly associated
with a good neonatal care support.
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