2012, Number 6
Central corneal thickness in juvenile glaucoma
Language: Spanish
References: 19
Page: 66-77
PDF size: 172.56 Kb.
ABSTRACT
Introduction: juvenile glaucoma is an uncommon variety and its clinical manifestations can simulate a primary glaucoma of open angle.Objective: to assess the behavior of central corneal thickness in juvenile glaucoma.
Material and Method: an analytical, longitudinal and prospective study was carried out including 29 patients suffering from juvenile glaucoma who attended to the specialized center of Ophthalmology at “Pepe Portilla” children hospital, Pinar del Rio from June 2010 to December 2011.
Results: the average age was 18, with a majority of male patients (51.72 %), and Caucasian, without statistical value. This figure (51.72 %) referred familial history of glaucoma; 93.10 % presented open angle glaucoma and 65.51% had a central corneal thickness inferior to 539 µm prevailing in this group a highly significant value of intraocular pressure between 22-25 mmHg was present in the 84.21% of them. No relationship was found between low-central corneal thicknesses and papillary-glaucoma alterations, a significant-statistical relationship among the values of intraocular pressure superior than 22mmHg and excavations greater than 0.5 with 92.85 % were found.
Conclusion: both sexes and races were equally affected prevailing patients suffering from open-angle glaucoma, family history was very important to establish the diagnosis; finding a significant association between the low corneal thickness and high figures of intra-ocular pressure not present in papillary glaucoma damage, which was related to high values of intra-ocular pressure.
REFERENCES
Turalba AV, Chen TC. Clinical and Genetic Characteristics of Primary Juvenile- Onset Open-Angle Glaucoma (JOAG). Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA, USA. Seminars in Ophthalmology. [Internet] 2008 [Citado 8 de abril 2011]; 23(1): [Aprox. 6p.]. Disponible en:http://www.ncbi.nlm.nih.gov/pubmed/18214788
Gordon MO, Beiser JA, Brandt JD, Heuer DK, Higginbotham EJ, Johnson CA, et al. The Ocular Hypertension Treatment Study: Baseline Factors that Predict the Onset of Primary Open-angle Glaucoma. Arch Ophthalmol. [Internet] 2002 [Citado 8 de abril 2011]; 120(6): [Aprox. 6p.]. Disponible en:http://www.ncbi.nlm.nih.gov/pubmed/12049575
Díaz Alemán VT, Fernández-Banca Vaca G, Lozano López V, García Somalo M, Perera Sanz D, González M. Nomograma de Riesgo de Progreso de Hipertensión Ocular Basado en el Ocular Hypertension Treatment Study. Arch Soc Esp Oftalmol. [Internet]. 2005 [Citado 8 de abril 2011]; 80(3): [Aprox. 4p.]. Disponible en:http://scielo.isciii.es/scielo.php?pid=S0365-66912005000300005&script=sci_arttext
Forsman E, Lemmela S, Varilo T, Kristo P, Forsius H, Sankila EM, et al. The role of TIGR and OPTN in Finnish glaucoma families: a clinical and molecular genetic study. Mol Vis. [Internet]. 2003 May-30 [Citado 8 de abril 2011]; 9: [Aprox.5p.]. Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/12789137
Béjar F, Olivares D, Cantero MA, Sánchez D. Grosor corneal central determinado mediante topografía corneal ORBSCAN en pacientes diagnosticados con glaucoma en población mexicana. Rev Sanid Milit. [Internet]. 2007 [Citado 19 de junio de 2011]; 61(5): [Aprox. 9p.]. Disponible en: http://www.imbiomed.com.mx/1/1/articulos.php?method=showDetail&id_articulo=46836&id_seccion=88&id_ejemplar=4743&id_revista=16
Alías EG, Ferreras A, Polo V, Larrosa JM, Pueyo V, Honrubia FM. Importancia del espesor corneal central en el estudio de hipertensos oculares, sospechosos de glaucoma y glaucomas preperimétricos. Sociedad Española de Oftalmología. [Internet]. 2007 Oct [Citado 19 de junio de 2011]; 82(10). Disponiblñe en:http://scielo.isciii.es/scielo.php?pid=S0365-66912007001000005&script=sci_arttext
Hong S, Kim CY, Seong GJ, Hong YJ. Central corneal thickness and visual field progression in patients with chronic primary angle-closure glaucoma with low intraocular pressure. Am J Ophthalmol. [Internet]. 2007 [Citado 19 de junio de 2011]; 143(2): [Aprox. 1p.]. Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/17258538
Stewart WC, Day DG, Jenkins JN, Passmore CL, Stewart JA. Mean intraocular pressure and progression based on corneal thickness in primary open-angle glaucoma. J Ocul Pharmacol Ther. [Internet]. 2006 [Citado 19 de junio de 2011]; 22(1): [Aprox. 7p.]. Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/16503772