medigraphic.com
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán

2008, Number 4

<< Back Next >>

Rev Invest Clin 2008; 60 (4)

Is there a shift in the epidemiology of Hepatitis A in Mexican children?

García-Juárez I, Solórzano SF, Álvarez-y-Muñoz MT, Vázquez-Rosales JG

Language: Spanish
References: 22
Page: 292-296
PDF size: 63.99 Kb.


ABSTRACT

Introduction. Twenty years ago, prevalence of Hepatitis A in Mexican children was 90%. Objective. To describe a shift in the prevalence of Hepatitis A virus (HAV) infection and to demonstrate an increment in the age at the first contact with HAV, in a sample of Mexican children. Material and methods. Reports of antiviral serologic studies collected from 1991 to 2005 from patients attending a pediatric hospital, were reviewed, and those with IgM anti-HAV positive in serum were selected. Age at the moment of acute infection was analyzed. Additionally, a serological survey searching IgG anti-HAV was made in a group of HAV unvaccinated children. Results. From 1,708 determinations of IgM, 221 were positive (13%). According to the year of report, five groups were constituted. Mean age by group was: 1991-1993 of 6.4 years, 1994-1996 of 8.0, 1997-1999 of 8.4, 2000-2002 of 8.0 and from 2003-2005 of 10.1 years. In a cohort of 259 unvaccinated children (mean of age 8.59 years), IgG antibodies were detected in 51%. Conclusion. In the infantile population studied a Hepatitis A epidemiology shift is suggested.


REFERENCES

  1. Ciocca M. Clinical course and consequences of Hepatitis A infection. Vaccine 2000; 18: S71-S74.

  2. Koff RS. Hepatitis A. Lancet 1998; 341: 1643-9.

  3. Pechevis M, Khoshnood B, Buteau L, Durand I, Piquard Y, Lafuma A. Cost-effectiveness of hepatitis A vaccine in prevention of secondary hepatitis A infection. Vaccine 2003; 21: 3556-64.

  4. Jacobs JR, Meyerhoff AS. Comparative cost effectiveness of Varicella, hepatitis A and Pneumococal Conjugate Vaccines. Preventive Medicine 2001; 33: 639-45.

  5. Willner IR, Uhl M, Howard SC, Williams EQ, Riely AC, Waters B. Serious Hepatitis A. Ann Intern Med 1998; 128: 111-19.

  6. Barzaga NG. Hepatitis A shifting epidemiology in South-East Asia and China. Vaccine 2000; 18: S61-S64.

  7. Cianciara J. Hepatitis A Shifting epidemiology in Poland and Eastern Europe. Vaccine 2000; 18: S68-S70.

  8. Tufenkeji H. Hepatitis A shifting epidemiology in the Middle East and Africa. Vaccine 2000; 18: S65-S67.

  9. Tanaka J. Hepatitis A shifting epidemiology in Latin America. Vaccine 2000; 18: S57-S60.

  10. Vitral CL, Gaspar AM, Souto FJ. Epidemiological pattern and mortality rates for hepatitis A in Brazil, 1980-2002. A review. Mem Int Oswaldo Cruz 2006; 101: 119-27.

  11. Albala C, Vio F, Yañez M. Epidemiological transition in Latin America: a comparison of four countries. Rev Med Chil 1997; 125: 719-27.

  12. World Health Organization. Weekly epidemiological record 2000; 75: 37-44.

  13. Bustamante CME, Correa B ME, Alvarez y Muñoz MT, Gómez JR, Muñoz HO et al. Etiología de la hepatitis en la ciudad de México. Bol Med Hosp Infant Mex 1986; 43: 5-10.

  14. Bustamante CME, Velásquez CF, Padilla N, Alvarez y Muñoz MT, Moreno AL, Martínez G et al. Seroepidemiología de la infección por el virus A de la hepatitis en comunidades de la frontera sur del estado de Chiapas. Bol Med Hosp Infant Mex 1986; 43: 735-41.

  15. Kumate J, Alvizouri A, Isibasi A. Encuesta serológica de hepatitis A en niños de México. Bol of Sanit Panam 1982; 92: 494-8.

  16. Bustamante CM, Ruíz G. Hepatitis A. Frecuencia de niños de cero a cinco años de edad. Gac Med Mex 1983; 119: 77-81.

  17. Calderón JE. Nuevos horizontes en el diagnóstico y prevención de la hepatitis viral. Bol Med Hosp Infant Mex 1986; 43: 731-4.

  18. De la Fuente JR. La salud en un México en transición. Salud Pública Mex 2004; 46: 164-8.

  19. Galicia LFJ. Frecuencia de parásitos oportunistas intestinales en niños con VIH/SIDA. Tesis para obtener el título de Químico Biólogo Parasicólogo. Instituto Politécnico Nacional. México. D.F., Agosto 2007.

  20. Valdespino JL, Olaiz G, López-Barajas MP, Mendoza L, Palma O, Tapia R, Sepúlveda J. Encuesta Nacional de Salud 2000. Tomo 1. Vivienda, población y utilización de servicios de salud. Cuernavaca, Morelos, México. Instituto Nacional de Salud Pública 2003.

  21. Centers for Disease Control and Prevention. Prevention of Hepatitis A through active or passive immunization. Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR 1999; 48(RR-12): 1-37.

  22. Centers for Disease Control and Prevention. ACIP’S 1996 Recommendations on the prevention of Hepatitis A through immunization. MMWR 1996; 45(RR-15): 1-27.




2020     |     www.medigraphic.com