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Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán

2009, Number 2

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Rev Invest Clin 2009; 61 (2)

Methicillin-resistant Staphylococcus aureus at a general hospital: epidemiological overview between 2000-2007

Álvarez JA, Ramírez AJ, Mojica-Larrea M, Huerta JR, Guerrero JD, Rolón AL, Medina H, Muñoz JM, Mosqueda JL, Macías AE, Sifuentes-Osornio J

Language: Spanish
References: 27
Page: 98-103
PDF size: 95.93 Kb.


ABSTRACT

Introduction. The high prevalence of methicillin-resistant Staphylococcus aureus (MRSA) in hospitalized patients is a significant problem due to its associated morbidity and mortality. It is important to know the recent MRSA epidemiology at a General Hospital. Objectives. To determine the MRSA epidemiology at a Mexican general hospital from 2000 to 2007, in order to know if there is a significant trend in its proportion. Material and methods. Prevalence survey. The resistance to oxacilllin was identified by the Kirby-Bauer’s method. The specimens were classified by type and year of isolation. Trend statistics were used for analysis. Results. S. aureus was identified in 1,008 samples, being 301 resistant to oxacillin (30%, 95% Confidence Interval [CI], 25 to 35%). The proportion of MRSA went from 37% (95% CI, 29 to 44%) to 49% (95% CI, 40 to 58%) in the period of study (χ2 for trends = 6.676, p ‹ 0.01). Specimens with the highest proportion of MRSA were blood and sterile liquids with 32% (95% CI, 26 to 39%), secretions with 29% (95% CI, 24 to 33%), and catheters with 21% (95% CI, 16 to 26%). Conclusions. The proportion of MRSA has increased significantly. This leads to higher costs and morbi-mortality for the hospitalized patients. We require stricter policies to prevent transmission and to control the use of antibiotics.


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