Confocal laser scanning microscopy and its association to the morphology of the filtering bleb

María Teresa Ferrer Guerra; Yuderkys Díaz Águila; Liamet Fernández Argones; Ibraín Piloto Díaz; Marerneda Domínguez Randulfe; Isabel Obret Mendive

2012, Number s1

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Rev Cub Oftal 2012; 25 (s1)

Confocal laser scanning microscopy and its association to the morphology of the filtering bleb

Ferrer GMT, Díaz ÁY, Fernández AL, Piloto DI, Domínguez RM, Obret MI

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ABSTRACT

Objective: to describe the findings in the confocal laser scanning microscopy and its relation with the morphology of the filtering bleb.
Methods: cross-sectional, observational and descriptive study of 100 eyes that underwent confocal laser scanning microscopy with the Retinal Heidelberg Tomography and the Rostock corneal module. Mc Nemar’s statistical significance test was made to obtain p=0,05.
Results: the 61-80 years old age group (55,8 %) and the caucasians predominated. The group of eyes with over 30 % decrease of the intraocular pressure showed the highest amount of filtering blebs of all sizes. The medium-size blebs were the ones that decreases the IOP in a higher percentage (24 eyes; 55,8 %) for p=0,00, followed by the small blebs (p=0,14). The flat blebs were predominant in 55 % of cases (p=0,00) and the 67,4 % of them were consistent with the major range of decrease of the intraocular pressure (p=0,01). The medium size blebs presented the major number of stromas in porous mesh (60 %), and of epithelial mycrocists (56 %) for p=0,00.
Conclusions: the flat configuration and the medium size of the blebs were related with the presence of the histological variables that infer adequate function of the filtrating blebs (stroma in porous mesh and epithelial mycrocists). They were also associated with higher decrease of intraocular pressure.

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