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Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán

2008, Number 2

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Rev Invest Clin 2008; 60 (2)

Mechanism of regulation of synthesis and secretion of human Chorionic Gonadotropin (hCG) during pregnancy

Barrera D, Chirinos M, García-Becerra R

Language: Spanish
References: 63
Page: 124-132
PDF size: 92.96 Kb.


ABSTRACT

Human chorionic gonadotropin (hCG) is an essential hormone for development and sustaining of gestation. Adequate hCG production is fundamental for pregnancy success since abnormal hCG serum concentrations have been correlated with pregnancy anomalies such as recurrent abortions and preeclampsia. Regulation of hCG production involves diverse molecules associated with different signaling pathways, which have complicated the establishment of the mechanisms involved in its production. The present study provides a critical review of the most relevant findings related to hCG production and functions during pregnancy, in order to help to understand some related pathologies and to treat them more adequately.


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