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2013, Number 1

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Rev Cub Med Mil 2013; 42 (1)

Importance of sucrose for healing infected wounds

Vizcaíno CM, Alarcón AI, Sebazco PC, Maceira CMA

Language: Spanish
References: 18
Page: 49-55
PDF size: 138.35 Kb.


ABSTRACT

Introduction: sucrose is a natural product that is considered for its bacteriostatic, bactericidal and stimulating healing characteristics. On the world market the sale of drugs and other products is dominated by monopolies, so it is necessary to evaluate an inexpensive alternative, which is able to reduce imports and which can be generally used.
Objectives: to assess the extent of total wound epithelialization and to identify sucrose actions on the dermis maturation degrees.
Methods: a clinical therapeutic randomized, controlled, unblinded study was performed in Wistar rats with induced infected skin lesions and, to assess the histological results of sucrose treatment of infected wounds.
Results: sucrose was effective in curing the infection in wounds and in promoting healing. There was complete wound epithelization six days in advance, in comparison with the control groups. better healing quality was achieved to reach with sucrose since a greater number of injuries reached grade III of dermis maturing.
Conclusions: better healing effect of sugar was demonstrated, as well as its antimicrobial activity due to its ability to clean wounds and to remove necrotic tissue. Higher degree of dermis maturation was achieved in those animals treated with sugar, which shows higher quality of healing in wounds treated with sugar.


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