Vázquez VMEF

Language: Spanish
References: 27
Page: 50-54
PDF size: 66.05 Kb.

ABSTRACT

Obesity is a key factor of metabolic syndrome and has been described as a public health problem in Mexico and industrialized countries. In order to treat obesity we need to understand the risk factors involved in the development of this illness. Leptin is the obesity gene product, which is the hormone responsible for maintaining energy homeostasis. The aim of this review is to describe the signaling pathway of leptin and participant mediators, as well as to determine pharmacological and nutritional perspectives for the treatment of leptin resistance that concurs with obesity.

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