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Boletín Clínico de la Asociación Médica del Hospital Infantil del Estado de Sonora

2012, Number 2

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Bol Clin Hosp Infant Edo Son 2012; 29 (2)

The Use of Imprint and Fine Needle Aspiration Biopsy in Early Malignancy Diagnosis.

Covarrubias-Espinoza G, Rivera-Gómez R, Rendón-García H

Language: Spanish
References: 18
Page: 53-57
PDF size: 53.25 Kb.


ABSTRACT

Introduction: The imprint and fine needle aspiration biopsy (FNB) are methods of quick, simple technique, minimum cost, with high sensitivity and specificity reports; that allows to give a diagnosis of malignancy in a manner more timely and thus start with a treatment specific early.
Material and Methods: Patients which underwent imprint or FNB in the Pediatric Oncology Service, in a period of 20 years were included. Washers, were analyzed as results were grouped into positive to benign and positive to malignancy. Histopathological results report obtaining values of sensitivity, specificity, predictive value positive (PPV) and negative predictive value (VPN) are subsequently corroborated.
Results: 121 cases entered, 88 (72.7%) were imprints and 33 (27.3%) FNAB. Reported to imprint a 92.1% sensitivity, specificity 91.6%, VPP 98.5% and VPN 64.7%; for the FNAB a 95.2% sensitivity, specificity 100%, 100% VPP and VPN 92.3%. The sensitivity for Hodgkin’s lymphoma was 87.5%, Wilms tumor 83.3%, 78.5% sarcomas and 75% liver tumors.
Discussion: The imprint and FNAB methods are procedures with high sensitivity, specificity and VPP for the diagnosis of malignancy. The negative predictive value is lower in the imprint technique. Sarcomas, Hodgkin’s lymphoma, Wilms tumor and liver tumors are the diagnostic with lower sensitivity. The main advantages of both procedures are speed, low cost, simplicity of procedure and high accuracy in the diagnosis of malignancy. The main disadvantage is the socket or improper sweep of the sample and the difficulty of performing these procedures in deep organs by the lack of desk studies of support in Pediatric Oncology Service.


REFERENCES

  1. 1.- Rivera Luna Roberto. El niño con Cáncer: Los padecimientos mas comunes para el médico no especialista. Editores de textos mexicanos, primera edición, 2007, cap. 1, 5 y 11.

  2. 2.- Sierrasesumaga L, calvo F, Villa-Elizaga I, Cañadell J. Oncología Pediátrica. Interamericana, primera edición, 1992.

  3. 3.- Pizzo Phipil A, Poplack David G. Principles and Practice of Pediatric Oncology. Lippincott, fifth edition, 2006.

  4. 4.- Suen K.C, Wood W.S, Syed A.A, Quenville N.F, Clement P.B. Role of Imprint Cytology in Intraoperative Diagnosis: Value and limitations. Journal of Clinical Pathology, 1978, 31; 328-37.

  5. 5.- Murillo Castillo Edgar. Biopsia por Aspiración con Aguja Delgada. Revista médica hondureña, 1998; 66: 24-30

  6. 6.- Yasunobu Funamoto, Masami Nagal, Reiji Haba,Masashi Ishikawa, Fujio Kishida, Kohoji Cono, et al. Diagnostic Accuracy of Imprint Cytology in the Assessment of Hodgkin‘s disease in Japan. Diagnostic cytopathology, 2005; 33: 20- 5.

  7. 7.- Barroso-Bravo S, Alvarado-Cabrero I, Mantilla A, Rojas ME, Nájera I, et al. El papel de la Impronta Transoperatoria en la Evaluación del Ganglio Centinela en Mujeres con Cáncer de Mama. Experiencia del hospital de oncología. Revista mexicana de mastología, vol1, No1 Octubre-Diciembre, 2006; 8-11.

  8. 8.- Mei-Hua Tsou, Mei-Ling Wu, Ai-Ying Chuang, Ching-Yuan Lin y Shyuang-Der Terng. Nasopharyngeal Biopsy Imprint Cytology: A retrospective analysis of 191 cases. Diagnostic cytopathology, 2006;34:204-7.

  9. 9.- Taneri F, Poyraz A, Salman B, Tekin E, Akyuerek N, et al. Using Imprint and Frozen Section in Determining the Surgical Strategies for Thyroid Pathologies. Endocrine regulation, 2001; 35:71-4.

  10. 10.- Issam M. Francis, Dilip K. Das. Role of Fine Needle Aspiration, Intraoperative Imprint Cytology and Frozen Section in the Diagnosis of Breast Lumps and Thyroid Lesions. Medical principles and practice, 1999;8:173-82.

  11. 11.- Hehn Sean T, Grogan Thomas M, Millar Thomas P. Utility of fine-needle aspiration as a diagnostic Technique in Lymphoma. Journal clinical oncology,2004; 22; 3046-52. 12.- Dilip K. Das. Value and Limitations of Fine-needle Aspiration Cytology in Diagnosis and Classification of Lymphomas: A review. Diagnostic cytopathology, 1999;21:240-9. 13.- Gamboa-Domínguez A, Luna-García L, Quintanilla-Martínez L. Biopsia de Ganglio Linfático con Aspiración con Aguja Delgada, correlación clínica y citohistológica en 179 casos. Revista de investigación clínica, 1995; 47: 35-41.

  12. 14.- Trutin-Ostovie K, Stanec S, Kumik G, Skoro M, Stanec Z. Intraoperative Imprint Cytology of Sentinel Lymph Nodes from Patients Witt Malignant Melanoma. Acta clinics, 2005;44:225-39.

  13. 15.- Drut Ricardo, Drut Rosa Mónica, Pollono Daniel, Tomarchio Silvia, Ibáñez Osvaldo et al. Fine-needle Aspiration Biopsy in Pediatric Oncology Patients. Journal pediatric hematology oncology, 2005; 27: 370-36.

  14. 16.- Braun Roth G, Calderón Elvir C, Ruano Aguilar JM. Biopsia por Aspiración con Aguja Delgada en Pediatría. Acta pediátrica mexicana, 1996; 17: 203-8.

  15. 17.- Taylor Suzanne R, Nuñez Carlos. Fine-needle Aspiration Biopsy in a Pediatric Population. Cancer, 1984; 54: 1449-53.

  16. 18.- Hahn PF, Eisenberg PJ, Pitman MB, Gazelle S.G, y Mueller P.R. Cytopathologic Touch Preparations (imprints) from Core needle Biopsies: Accuracy compared with that of fine-needle aspiration. American journal of pathology, 1995; 165:1277: 9.

  17. 19.- Liu Yulin, Silverman J.F, Sturgis C.D, Brown H.G, Dabbs D.J, et al.Utility of Intraoperative Consultation Touch Preparations. Diagnostic cytopathology 2002; 26: 329-33.

  18. 20.- Millar AJW, Sinclair-Smith C, Rode H, Hartley P, Karabus C, et al. Fine-needle Cytology of Solid Tumors: Method, diagnostic accuracy, and role in management- Journal of pediatric surgery, 1990; 25: 1088-91.




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