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2005, Number 4

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Rev Mex Anest 2005; 28 (4)

Comparative study of two sedation methods for axillary blockade in pediatric patients, ketamine vs. sevoflurane

Zaragoza-Lemus G, Sánchez-Velasco B, Gonzáles-Flores L, Unzueta-Navarro D, Peralta-Zamora E, Mendoza-Jiménez M

Language: Spanish
References: 20
Page: 192-197
PDF size: 63.46 Kb.


ABSTRACT

Objective: To compare sedation obtained using either ketamine or sevoflurane in pediatric patients subject to hand surgery under axillary brachial plexus blockade. Materials and methods: A randomized, prospective study was carried out in 100 pediatric patients (6 months to 12 years old) scheduled for elective hand and forearm surgery. Patients were randomly assigned to one of two groups; the “K Group” was given ketamine 2 mg/kg body weight, whereas the “S group” received sevoflurane 2v%. Immediately, an axillary blockade was performed, with nerve stimulator and local anesthetic. Patients were kept on spontaneous ventilation at 40% FiO2. A sedation scale and a pain scale were recorded after surgery. Results: There were no demographic differences among groups. Intraoperative hemodynamic records showed an increased heart rate in the K group (p = 0.1154), whereas time to awakening and pain scores showed no significant differences. Sedation scores were significantly lower in the S group both at 5 and 15 minutes (p ‹ 0.05). Adverse events in the K group included vomit in 2 cases and persistent nistagmus in 16 cases. Conclusions: Sevoflurane appeared to achieve a superior sedation than ketamine, with no side effects.


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