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1999, Number 2

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Rev Med Hosp Gen Mex 1999; 62 (2)

Gallbladder carcinoma: An underestimate neoplasia

Aristi UG, Pérez-Peña Díaz-Conti M, Soto AMV

Language: Spanish
References: 61
Page: 94-101
PDF size: 206.96 Kb.


ABSTRACT

Gallbladder carcinoma is or underestimated importance in Mexico due to a high frequency of diagnostic error, unknown epidemiology, and a decrease in autopsy practice to confirm the cause of death. This is a retrospective study of 4769 consecutive autopsies to compare the frequency of gallbladder carcinoma with other digestive tract carcinomas. Our results suggest that gallbladder carcinoma a very common entity. It was the principal cause of death of all malignant tumors of the digestive tract: in general (25.8%), and in women (34.6%). The clinical diagnosis was incorrect in 69%. Autopsy is mandatory to have a real idea of its frequency. It is a mistake to consider gallbladder carcinoma and extrahepatic bile duct carcinoma as the same entity, because they have considerable clinico-pathological differences. Although it is very likely that there is genetic susceptibility for gallbladder carcinoma in indian and mixed population in the country, pathogenesis is still a mystery.


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