Aristi UG, Pérez-Peña Díaz-Conti M, Soto AMV

Idioma: Español
Referencias bibliográficas: 61
Paginas: 94-101
Archivo PDF: 206.96 Kb.

RESUMEN

El carcinoma de vesícula biliar es una neoplasia subestimada en nuestro país, principalmente por tres razones: elevada frecuencia de error diagnóstico, epidemiología poco conocida y decremento en la práctica de autopsias que confirmen la causa de muerte. Hicimos un estudio retrospectivo de 4,769 autopsias consecutivas para comparar la frecuencia del carcinoma de vesícula biliar con el resto de carcinomas de tubo digestivo. Nuestros resultados indican que este tumor es muy frecuente. Ocupó el primer lugar como causa de muerte sobre el resto de neoplasias malignas del tubo digestivo: en general (25.8% del total), y en mujeres (34.6%). El diagnóstico clínico fue incorrecto en el 69% de los casos. La autopsia es obligada si deseamos tener una idea real sobre su frecuencia. Es un error considerar al carcinoma de vías biliares extrahepáticas y al carcinoma de vesícula biliar como una misma entidad, pues tienen diferencias clinicoepidemiológicas considerables. Aunque es muy probable que exista susceptibilidad genética para el carcinoma de vesícula biliar en la población indígena y mestiza del país, la etiopatogenia de esta neoplasia continúa siendo un misterio.

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