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2013, Number 1

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Med Crit 2013; 27 (1)

Calibration and discrimination of APACHE II and APACHE IV

Castañeda-Morales VM, Sánchez-Velázquez LD, Jiménez-Garduño NM

Language: Spanish
References: 25
Page: 8-14
PDF size: 100.84 Kb.


ABSTRACT

Objective: The aim was to determine discrimination and calibration of APACHE II and APACHE IV in critical patients of the General Hospital of Mexico.
Design: A comparative, descriptive longitudinal prospective cohort.
Setting: Intensive care units of different specialties in the General Hospital of Mexico.
Patients: A total of 546 patients were included and analyzed.
Interventions: None.
Measurements and principal results: Observed mortality was 40.8%, the predicted mortality by APACHE II and APACHE IV were 21.1% and 15.8%, respectively. The standardized mortality ratio for APACHE II and APACHE IV were 1.93 and 2.58, respectively. Calibration values of APACHE II and IV were 11.456 (p = 0.120) and 3.802 (p = 0.875), respectively. The discrimination (area under ROC) of APACHE II and IV was 0.770 ± 0.020 (IC95% 0.730-0.810) (p ‹ 0.001) and 0.770 ± 0.021 (IC95% 0.730-0.810) (p ‹ 0.001), respectively.
Conclusions: Both scores showed good performance in the intensive care units of the General Hospital of Mexico for predicting mortality.


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