Gómez-Toscano V, Hernández-Orozco HG, González-Saldaña N, Castañeda-Narváez JL, Rosas-Ruíz A, Sandoval-Medina MC, Leticia Aparicio-Santiago GL

Language: Spanish
References: 17
Page: 16-20
PDF size: 178.42 Kb.

ABSTRACT

Hospital outbreaks by B. cepacia are common in immunocompromised patients. This requires early vigilance for this pathogen in the hospitals and the need to understand its intrinsic and extrinsic characteristics in order to enable its early detection and to apply immediate control measures for this pathogen. We present two cases of bacteremia B. cepacia seen in the Oncology Department. We concluded that a contact transmitted outbreak was highly suspicious.

REFERENCES

1. Pickering LK, Baker CJ, Baltimore RS, Boechini JA, Fisher MC, Gerber MA. Red Book. Enfermedades Infecciosas en Pediatría. 28 ed. Ed. Médica Panamericana; 2011. p. 237-9.

2. Engelkirk PG, Duben-Engerkirk J. Laboratory Diagnosis of Infectious Diseases. Lippincott Williams and Wilkins; 2008. p. 328-31.

3. Navarrete S, Muñoz O, Preciado IS. Infecciones intrahospitalarias en Pediatría. McGraw-Hill Interamericana; 1998. p. 56.

4. Mann T, En-David D, Zlotkin A, Shachar D, Keller N, Toren A, et al. An outbreak of Burkholderia cepacia bacteremia in immunocompromised oncology patients. Infection 2010;38(3):187-94.

5. Centers of Disease Control. Steps of an outbreak investigation. In: www.cdc.gov./excite/classroom/outbreak/steps.htm Acceso Nov 2011.

6. Goering RV. Pulsed-field electrophoresis. In: Molecular Microbiology: Diagnostic Principles and Practice. 8th ed. American Society for Microbiology; 2004. p. 185-96.

7. Heo ST, Kim SJ, Jeang YG, Bae IG, Jin JS, Lee JC. Hospital outbreak of Burkholderia stabilis bacteraemia related to contaminated chlorhexidine in haematological malignancy patients with indwelling catheters. J Hosp Infect 2008;70(3):241-5.

8. Hoste B, De Vos P, Henry D, Speert DP, Vadamme , Mahenthiralingam E. Burkholderia cepacia (formerly Genomovar IV Burkholderia stabilis) sp. nov. J Clin Microbiol 2000;38(3):1042.

9. Weber DJ, Rutala WA, Sickbert-Bennett EE. Outbrake Associated with contaminated antiseptics and disinfectants. Antimicrob Agents Chemother 2007;51(12):4217-24.

10. Doit C, Loukil C, Simon AM, Ferroni JE, Fontan JE, Ferroni A. Outbrake of Burkholderia cepacia bacteremia in a pediatric hospital due to contamination of lipid emulsion stoppers. J Clin Microbiol 2004;42(5):2227-30.

11. Ghazal SS, Al-Mudaimeegh K, Mohammed E, Fakihi A, Talee AA. Outbrake of Burkholderia cepacia bacteriemia in inmunocompetent children caused by contaminated nebulized sulbutamol in Saudi Arabia. Am J Infect Control 2006;39:394-8.

12. Lee JK. Two Outbrake of Burkholderia cepacia nosocomial infections in a neonatal intensive care unit J Pediatric Child Health 2008;44:62-6.

13. Hamill RJ, Houston ED, Georghiou PR, Wright CE, Koza MA, Cadle RM. An outbreak of Burkholderia cepacia respiratory tract colonization and infection associated with nebulized albuterol therapy Ann Intern Med 1995;122:762-6.

14. Kotsanas D, Brett J, Kidd TJ, Stuart RL, Korman TM. Disinfection of Burkholderia cepacia complex from non-touch taps in a neonatal nursery. J Perinat Med 2008;36(3):235-9.

15. Cardoso-Hernández G, De Colsa –Ranero A, Zepeda-Orozco G, Arzate-Barbosa P, González Saldaña N. Burkholderia cepacia en niños. Rev Enf Infec por Burkholderia cepacia en niños. Rev Enf Infec Pediatr 2007;20(80):92-8.

16. González SN, Hernández OHG, Castañeda NJL, Arzate BP, Lombardo AE, Girón HJA. Brotes de Burkholderia cepacia en el Instituto Nacional de Pediatría. Acta Pediatr Mex 2008;29(4):185-8.

17. Sánchez HG, González SP, Hernández OHG. Confirmación de un brote de bacteriemia por Burkholderia cepacia en una unidad de cuidados intensivos pediátricos mediante biología molecular. Tesis para obtener el diploma de especialista en Infectología Pediátrica. Instituto Nacional de Pediatría. 2010.