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2000, Number 2

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Rev Med Hosp Gen Mex 2000; 63 (2)

Retropubic radical prostatectomy in the treatment of the in situ prostatic carcinoma.Experience at the Hospital General de México

Manzanilla-García HA, Torres-Saunders C, Gutiérrez-Godínez FA, Castañeda-Sánchez JJ, Hernández M, Martínez-Mejía JB

Language: Spanish
References: 34
Page: 91-97
PDF size: 267.48 Kb.


ABSTRACT

Introduction. The radical retropubic prostatectomy is a therapeutic procedure that has demonstrated to have benefit in the treatment of patients with prostate cancer in its stages confined to the organ. In our Country this treatment method is not still of the domain of the whole urologic community. Objectives. To communicate the experience of the treatment of organ confined prostate carcinoma, in our hospital, with this surgical procedure. Material and method. The files of 72 subjected patients were revised to this surgical procedure, of which 53 were selected. To all the patients were studied age, clinical and pathological stage, Gleason´s score, prostatic specific antigen (PSA) before and after the procedure, complications and global survival as well as free-disease survival. Results. It was an important difference in the clinical and the pathological stadification; alone 25 (47%) patients presented tumor confined at the organ and 28 (53%) presented data of infiltration of the periprostatic tissue. The histopathological degree had a directly proportional relationship to the definitive pathological stage as well as with the biological behavior of the tumor. The value of the postoperative PSA showed values smaller than 0.2 ng/mL in those patients with control of the disease. The follow-up of the patients was of 38.1 months. A global survival of 90.5% was seen. The global free-disease survival was of 65%. Those patients with disease confined to the organ had a free-disease survival of 88%, and only of 39% for patient with locally advanced disease. Conclusions. The radical retropubic prostatectomy demonstrated to be a very useful procedure for the treatment of the prostate carcinoma confined to the gland in the studied population. The current diagnosis methods, still allow a high percentage of under-stadification of patient with this disease. The free-disease survival is directly related with the definitive stage of the disease.


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