2012, Number 4
<< Back Next >>
Correo Científico Médico 2012; 16 (4)
Chronic antral gastritis for Helicobacter pylori and gastroesophageal reflux disease
Mulet PAM, Gámez EMM, Tamayo OM, Escobar BA, Pozo AH, Verdecia CAM
Language: Spanish
References: 16
Page:
PDF size: 343.18 Kb.
ABSTRACT
Background: The chronic antral gastritis for Helicobacter pylori (H pylori) and gastroesophageal reflux disease (GERD) are frequent affections that can coexist. The possible influence of the infection for H pylori on the GERD is a controversial theme.
Objectives: Estimating the histopathological behavior of the chronic antral gastritis for H pylori according to the presence or no of GERD with and without oesophagitis. Methods: Case-control study. Universe: the total of patients attended during January 2008- January 2009 in Gastroenterología's Service of the Teaching Hospital of Holguín, with endoscopy and gastric antral diagnostic biopsy of chronic antral gastritis and infection by H pylori. Two samples: A study group with GERD’s symptoms (38 patients); control group without GERD (59 patients).
Results: Bigger significant proportion of chronic antral quiescent gastritis in the patients with GERD, 11 (0.2895), group control, 3 (0.0508). The moderate severe grade of lesion in both groups predominated: I study, 29 (0, 7632), control, 51(0.8644), without significant difference. Preponderated the density moderated abundantly of colonization by H pylori in both groups, study 20(0.5263) and control 43(0.7288), with significant difference in favor of the last. The density moderated abundantly predominated in the GERD without oesophagitis without significant difference of the GERD with oesophagitis.
Conclusions: The bigger proportion of chronic antral quiescent gastritis in the patients with GERD and the predominance of the abundant density and moderated of the colonization for H pylori in the patients without GERD they back up the possibility of a protective effect of H pylori against the GERD.
REFERENCES
1 Naumovski Mihali S, Sabari B, Filipec T, Tiak M, Prskalo M, Skurla B, et al. Gastroesophageal reflux disease and Helicobacter pylori infection .Lijec Vjesn. 2002; 124 (Sup1):52-6.
2 Öberg S, Peters MJF, Nigro JJ, Theisen J, Hagen JA, DeMeester SR. Helicobacter pylori is not associated with the manifestations of gastroesophageal reflux disease. Arch Surg. 1999; 134:722-6.
3 González Carbajal PM. Helicobacter pylori, dispepsia, enfermedad esofágica por reflujo y cáncer de esófago. Helicobacter pylori: ¿El tercer dogma? Madrid: Editorial Autores Productores Asociados; 2003.
4 Gámez Escalona M, Mulet Pérez A, Borrero Cobas J, Mulet Gámez A. Gastritis crónica antral por Helicobacter pylori. Correo Cient Méd. 2005 [citado 24 abr 2012]; 9(2). Disponible en: http://www.cocmed.sld.cu/no92/n92ori5.htm
5 Gámez Escalona M, Mulet Pérez A, Miranda Moles Z, Mulet Gámez A. Gastritis crónica antral por Helicobacter pylori en la infancia. Rev Cub Pediatr. 2008 [citado 24 abr 2012]; 80(1).Disponible en: http://scielo.sld.cu/scielo.php?script=sci_pdf&pid=S0034-75312008000100002&lng=es&nrm=iso&tlng=es
6 Gámez Escalona M, Mulet Pérez A, Gamboa Figueredo J, Mulet Gámez A. Gastritis crónica antral por helicobacter pylori asociada o no a úlcera gástrica. Correo Cient Méd. 2005 [citado 24 abr 2011]; 9(3).Disponible en: http://www.cocmed.sld.cu/no93/n93ori7.htm
7 Mulet Pérez A, Gámez Escalona M, Medina Menéndez F, Mulet Gámez A. Gastritis crónica antral por Helicobacter pylori asociada o no a úlcera duodenal. Correo Cient Méd. 2005 [citado 24 abr 2012]; 9(2). Disponible en: http://www.cocmed.sld.cu/no92/n92ori10.htm
8 Fenoglio Preiser C. Creating a framework for diagnosing the bening gastric biopsy. Curr Diag Pathol. 1998; 5(1):2-16.
9 Massey BT. The implications of Helicobacter pylori infection for gastroesophageal reflux disease: studies presented at Digestive Disease Week 2003. Curr Gastroenterol Rep. 2004 [citado 24 abr 2012]; 6(3):191-5.
10 Peitz U, Vieth M, Malfertheiner P. Carditis at the interface between GERD and Helicobacter pylori infection. Dig Dis. 2004; 22(2):120-5.
11 Haruma K, Manabe N, Kamada T, Shiotani A, Kusaka K. Helicobacter pylori infection and GERD. Nihon Rinsho. 2007 [citado 24 abr 2012]; 65(5):841-5.
12 Sarnelli G, Ierardi E, Grasso R, Verde C, Bottiglieri ME, Nardone G, et al. Acid exposure and altered acid clearance in GERD patients treated for Helicobacter pylori infection. Dig Liver Dis. 2003; 35(3):151-6.
13 Jonaitis LV, Kiudelis G, Kupcinskas. Characteristics of patients with erosive and nonerosive GERD in high-Helicobacter-pylori prevalence region. Dis Esophagus. 2004; 17(3):223-7.
14 Chourasia D, Misra A, Tripathi S, Krishnani N, Ghoshal UC. Patients with Helicobacter pylori infection have less severe gastroesophageal reflux disease: a study using endoscopy, 24-hour gastric and esophageal pH metry. J Gastroenterol. 2011; 30(1):12-21.
15 Somi MH, Fattahi E, Fouladi RF, Karimi M, Bonyadi R, Baballou Z. An inverse relation between Caga strains of Helicobacter pylori infection and risk of erosive GERD. Saudi Med J. 2008; 29(3):393-6.
16 Klitorakis I, Stanciu C. Prevalence of Helicobacter pylori infection in patients with gastroesophageal reflux disease. Rev Med Chir Soc Med Nat Lasi. 2010; 114(1):80-4.