Pale-Torres LJ, Lozano-Nuevo JJ, Rubio-Guerra AF

Language: Spanish
References: 12
Page: 311-314
PDF size: 30.82 Kb.

ABSTRACT

Background: both, the ankle-braquial index ‹ 0.9, and microalbuminuria are considered markers of endothelial dysfunction. Our objective was to evaluate if there is a correlation between the ankle-brachial index (ABI) and the degree of albuminuria in diabetic normotensive patients.
Methods: we included 32 diabetic normotensive patients and measured their ABI, and their 24-h urinary albumin excretion by nephelometry; the ABI and albuminuria were correlated with the Spearman correlation coefficient.
Results: we did not find overall correlation between the ABI and albuminuria (r = 0. 21, 95 % CI = –0.14-0.52, p = 0. 12); However, when we measured the correlation of an ABI ‹ 0.9 with any degree of albuminuria, we found a significant correlation (r = –0. 32 ± 0. 11, 95 % CI = 0.027 to –0.6, p = 0. 03); and when the correlation of ABI with albuminuria > 300 mg, we also found a significant correlation (r = –0.45 ±, 0.11, 95 % CI = –0.015 a –0.76, p = 0. 03).
Conclusions: our results suggest that ABI ‹ 0.9 is a useful marker to estimate microalbuminuria in diabetic normotensive patients.

REFERENCES

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