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2011, Number 6

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Rev Med Inst Mex Seguro Soc 2011; 49 (6)

Incidence and risk factors associated with in-hospital sepsis

Tijerina-Torres CY, Rodríguez-Balderrama I, Gallegos-Dávila JA, Cavazos-Elizondo M, Romero-Rocha JA

Language: Spanish
References: 25
Page: 643-648
PDF size: 41.35 Kb.


ABSTRACT

Background: inhospital neonatal sepsis (IHNS) is a clinical syndrome characterized by an inflammatory reaction with local or systemic signs of infection, accompanied by the causal agent in the first month of life. The objective was to know the incidence and risk factors associated with IHNS.
Methods: during 2006 and 2007 were included a total of 49 patients in the case group and 50 patients in the control group. A serie of qualitative variables comparing the two groups to determine their association were analyzed.
Results: It was found an incidence of IHNS in our hospital of 3.7 %. The most frequently observed risk factors were: birth weight in the trophic group between 1501-2500 g, and in the hypotrophic group, the use of central vascular access, ranitidine, steroids, parenteral nutrition, endotracheal intubation, orogastric catheter, vesical catheter, and also the presence of cardiopathy or hyaline membrane disease (HDM). The mortality rate was 24.4 %.
Conclusions: the incidence of IHNS was less than reported in the literature. The death associated with IHNS was low.



REFERENCES

  1. Zaidi AK, Huskins WC, Thaver D, Bhutta ZA, Abbas Z. Hospital- acquired neonatal infections in developing countries. Lancet 2005;365(9465):1175-1188.

  2. Eraso J, Troncoso G, Álvarez M, Ibáñez M. Comportamiento epidemiológico de la sepsis nosocomial en la Unidad de Recién Nacidos de la Fundación Cardioinfantil. Rev Cienc Salud 2008;6(1):36-49.

  3. Behrman RE, Kliegman RM, Jenson HB. Infecciones del RN. En: Behrman RE, Kliegman RM, Jenson HB, editores. Nelson. Tratado de pediatría. Décima quinta edición. Madrid: McGraw-Hill-Interamericana; 1988. p. 643-676.

  4. Lott JW. Neonatal bacterial sepsis. Crit Care Nurs Clin North Am 2003;15(1):35-46.

  5. Schaffer AJ, Taeusch HW, Ballard RA, Avery ME. Infecciones virales en el feto y el recién nacido. En: Schaffer AJ, Taeusch HW, Ballard RA, Avery ME, editores. Enfermedades del recién nacido. Sexta edición. Philadelphia: Panamericana; 1993. p. 357-375.

  6. Polin RA, Fox WW, Abman SH. Fetal and neonatal physiology. Third edition. Philadelphia: Elsevier Saunders; 2004. p. 1475-1486.

  7. Saiman L. Risk factors for hospital-adquired infections in the neonatal intensive care unit. Semin Perinatol 2002;26 (3):315-321.

  8. Rosas JV, Gutiérrez VH, Gutiérrez J. Factores de riesgo en sepsis neonatal en un hospital de tercer nivel en la ciudad de México. Rev Esp Med Quir 2005;10(2):21-24.

  9. Adams I, Stoll BJ. Prevention of nosocomial infection in the neonatal intensive care unit. Curr Opin Pediatr 2002; 14(2):157-164.

  10. López J, Coto GD, Ramos A, Fernández B. Reflexiones en torno a la infección en el recién nacido. An Esp Pediatr 2002;56(6):493-496.

  11. Ochoa CE, Rodríguez BI, Miranda BI, Ábrego MV. Análisis de mortalidad neonatal en un Hospital Universitario (Dr. José Eleuterio González) de tercer nivel de atención. Medicina Universitaria 2006;8(33):207-211.

  12. Taeusch HW, Ballard RA, Gleason CA. Avery´s diseases of the newborn. Eighth edition. Philadelphia: Elsevier; 2005. p. 1-8, 578-600.

  13. Harris MC, Polin RA. Diagnosis of neonatal sepsis. En: Spitzer AR, editor. Intensive care of the fetus and neonate. 2nd. ed. Philadelphia: Elsevier Mosby; 2005. p. 1115-1123.

  14. Polin RA, Saiman L. Nosocomial infections in the neonatal intensive care unit. Neoreview 2003;4(3):81-87.

  15. Bellantine J. Inmunología del feto y del recién nacido. En: Tratado de neonatología de Avery. Séptima edición. Madrid: Harcourt Saunders; 1987. p. 857-878.

  16. Pikering B. Gerber Informe del Comité de enfermedades infecciosas de la American Academy of Pediatrics. Red Boock. 25th. ed. London: Panamericana; 2002. p. 513.

  17. Badawi N, Kuninczuk JJ, Keogh JM, Elessandri LM, O´Sulli-van F. Intrapartum risk factors for newborn encephalo-pathy: the Western australian case-control study. Br Med 1998; 317(7172):1554-1558.

  18. Carrera G, Liberatore A, Arena S, Minili I. Percutaneous central IV access in the neonate: a simplified approach. Acta Paediatr 1996;85(11):1385-1386.

  19. Montilla I. Ranitidina como tratamiento para el reflujo gastroesofágico en neonatos. Rev del CNEM 2009;1:1-4.

  20. Stein CM, Pincus T. Glucocorticoids. En: Kelly W, Harris E, Shaun R, Sledge C, editores. Rheumatology. Cuarta edición. Philadelphia: WB Saunders Company; 1997. p. 787-803.

  21. Polin AR, Saiman L. Nosocomial infections in the neonatal intensive care unit. Neoreview 2003;4(4):81-89.

  22. Rojas MA. Risk factors for nosocomial infections in selected neonatal intensive care units in Colombia, South America. J Perinatol 2005;25:537-541.

  23. Serrate G, Canals M, Fontanals D, Segura F, Torremorell D, Nogueras A. Prevalencia de infección urinaria nosocomial. Medidas alternativas al cateterismo vesical. Med Clin 1996;107:241-245.

  24. Buchman AL. Parenteral nutrition is associated with intestinal morphologic and functional changes in humans. JPEN J Paenter Enteral Nutr 1995;19:456-460.

  25. Brent Carter A, Hornick D. Pneumonia: Therapy for ventilator— associated pneumonia. Clin Chest Med 1999;20(3):40-45.




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