Tavares E, Alves R, Viana I, Vale E

Language: Portugués
References: 16
Page: 76-85
PDF size: 242.71 Kb.

Text Extraction

Introduction and aims: Sebaceous tumours are uncommon lesions whose classification and diagnosis are sometimes difficult. The authors conducted a retrospective study of sebaceous tumours diagnosed in the Department of Dermatopathology, for a period of 10 years (between January 2001 and December 2010).
Materials and methods: We evaluated clinical (age at diagnosis, sex, anatomical location and proposed clinical diagnosis) and histopathological parameters (circumscription, symmetry, location, connection with epidermis, proportion of sebaceous and germinative epithelium, architectural pattern, presence of cysts, vascular invasion and cellular pleomorphism, mitosis and inflammatory infiltrate]. Only adenoma, sebaceoma and sebaceous carcinoma were included.
Results: A total of 42 tumours, corresponding to 38 patients, 24 male and 14 female, were included in this retrospective study. The overall mean age was 66.3 years. The most frequent group was sebaceous adenoma (n = 25), followed by sebaceoma (n = 13) and sebaceous carcinoma (n = 4). We observed lesions with particular architectural patterns associated with Muir-Torre syndrome. The head was the mainly affected region for sebaceous adenoma and epithelioma. All cases of sebaceous carcinoma were extra-ocular. Basal cell carcinoma was the most commonly cited clinical diagnosis.
Comments: There was predominance of sebaceous adenoma, male gender, older age and the head was the main location. The assent between clinical and histological diagnoses was rarely observed.

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