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2011, Number 6

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Rev Med Inst Mex Seguro Soc 2011; 49 (6)

Pregnancy outcomes, before and after rheumatoid arthritis on set

Álvarez-Nemegyei J, Cervantes-Díaz MTJ, Ávila-Zapata F, Marín-Ordóñez J

Language: Spanish
References: 26
Page: 599-604
PDF size: 35.96 Kb.


ABSTRACT

Objective: to compare the obstetric prognosis before and after rheumatoid arthritis (RA) onset.
Methods: a survey in RA women patients that become sexually active before disease onset, and who tried or got pregnant after diagnosis was performed. Obstetrical features such as: number of pregnancies, abortion menace, abortion, early natal death, congenital abnormalities and preeclampsia-eclampsia syndrome, before and after RA onset were compared.
Results: only 47 (age: 40.5 ± 11.0 years; time of evolution: 15.9 ± 11.5 years; positive rheumatoid factor: 93.6 %) women were eligible from 700 screened. After RA onset there were 63 gestations in 36 patients which got pregnant (secondary infertility rate: 21.3 %). A significant increase in frequency and number of cesarean deliveries, besides a higher number of pregnancies with preeclampsia were found after RA onset. Additionally, four newborns with congenital anomalies were reported after the disease onset compared to none before AR onset.
Conclusions: compared to pre-RA obstetric path, a higher frequency and number of adverse outcomes was found in pregnancies that occurred after RA onset.



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