Díaz PAL, Campos GJ

Language: Spanish
References: 15
Page: 127-135
PDF size: 461.45 Kb.

ABSTRACT

Bacteria of the Pseudomonas genus possess the ability to grow in a variety of organic compounds using them as a source of carbon and energy. These include isoprenoids, which are very stable compounds and ubiquitous. Biodegradation of isoprenoids is influenced by its structure, being the 2-methyl branched compounds more susceptible than the 3-methyl branched. Microbial strategies for removing the 3-methyl branching group in the isoprenoids involves its carboxylation, generating an acetyl group capable of being hydrolyzed. The acyclic isoprenoid degradative pathway has been elucidated in Pseudomonas aeruginosa and Pseudomonas citronellolis using citronellol, geraniol or farnesol as model compounds. This is constituted by four stages: (i) oxidation-activation upper pathway, (ii) acyclic terpenes (ATU) central pathway, (iii) coupling of the β oxidation, and (iv) convergence to leucine/isovalerate (LIU) pathway. End products of these stages are channeled to the tricarboxylic acid cycle and glyoxylate.

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