Mariscal MLF, Navarro MC, Montañez DLTI, Solano SR, Contreras RA, González CJ, Aguinaga RM

Language: Spanish
References: 14
Page: 307-313
PDF size: 47.87 Kb.

ABSTRACT

Chromosome abnormalities are the leading cause of pregnancy loss in the first trimester, accounting for 60-70% of cases, the most frequently reported aneuploidy are autosomal trisomies, being 16, 22, 13 and 15 the highest incidence, followed of polyploidy, monosomy, and other abnormalities. We studied 182 cases of abortion in our clinic with a diagnosis of 1ry or 2ry infertility that underwent curettage and 126 of them with subsequent cytogenetic study. The results showed a higher incidence of autosomal trisomies, where 22 was the most common, followed by 21 and 16, the maternal age average was 34.35 years, mainly determined by the type of people who come to our clinic, the average gestational age was 9.5 weeks, showing an important priority for the first trimester. From all studied cases, 103 were spontaneous pregnancies, 33 instrumental uterine insemination and 46 in vitro fertilization. Couples are starting later and later their reproductive life, increasing the incidence of chromosomal loss causes. Genetic studies of all gestational losses are essential to identifying the cause, and give proper couple reproductive advice, adequate treatment and prevent recurring losses.

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