2012, Number 3
<< Back Next >>
Arch Med Urg Mex 2012; 4 (3)
Toxic plants: Brugmancia (floripondio) neurotoxicity
Pérez BE, Rodríguez OR, Sánchez VMC
Language: Spanish
References: 12
Page: 119-124
PDF size: 399.32 Kb.
ABSTRACT
There are a variety of plants that can be toxic to humans, unfortunately many of them can be used intentionally to produce various types of effects on the body and the indiscriminate use and lack of toxicological information about them by the population, can lead to severe organic lesions and even death. Many of the plants that are sometimes used therapeutically are sold without restriction in different markets and herbal stores, leading to abailability and use. It may cause toxic effects of varying severety depending on dose and mode of administration. Some of them are kept as ornamental plants by many people in our country, being well in gardens, parks and flower pots in many houses, of which an example is the Brugmancia that although there is no known toxic dose, can cause significant neurological damage, so the aim of this paper is to report a case of the neurotoxic effects of the plant and disseminate among the medical community the importance of detecting toxindrome caused by the substances of this flower so we can provide appropriate multidisciplinary management to achieve lower morbidity and mortality of plant poisoning. The Brugmancia (floripondio) has scopolamine, chemical substance found throughout the plant that produces neurological changes among other alkaloids that induce a clinical picture of neurotoxicity that can lead to death.
REFERENCES
Nogué S, Antolin A, Claramonte X y cols. Urgencias por sobredosis de drogas, Sección de Toxicología Clínica y Servicio de Urgencias. Hospital Clinic. Barcelona. Área Científica Menarini, 2008.
Mencías RE, Mayero FLM. Manual básico de toxicología. Editorial Díaz de Santos, Madrid, España. 2000; 8: 285-307.
Aroukou H, Matray MD, Bragança C, Mpaka JP et al. Voluntary poisoning by ingestion of datura stramonium. Another cause of hospitalization in youth seeking strong sensations. Ann Med Int 2003; 154: 1S46-1S50.
Evens RP, Leopold JC. Scopolamine toxicity in a newborn. Pedriatics 1980; 66(2): 329-330.
Smith EA, Meloan CE, Pic JA. Scopolamine poisoning from homemade moon flower wine. J Anal Toxicol 1991; 15(4): 216-219.
Iranbakhsh A, Ali Oshaghi M, Majd A. Distribution of atropine and scopolamine in different organs and stages of development in datura stramonium l. (solanaceae). Structure and ultrastructure of biosynthesizing cells. Polish Academy of Sciences, Cracow 2006; 48(1): 13-18.
Abdelouahab Bouzidi, Nadia Mahdeb and Nabila Kara, Toxicity studies of alkaloids of seeds of Datura stramonium and synthesis alkaloids in male rats. J Med Plant Res 2011; 5(5): 3421–3431.
Harris CR. Manual de toxicología para médicos. Rabdomiólisis. Editorial Elsevier Masson, Barcelona 2008: 19.___
Net CA, Marruecos–Sant L. Intoxicaciones agudas graves; Intoxicaciones por plantas Editorial Ars Médica, Madrid, Barcelona, 2006; 21: 287-306.
Artal FC. Síndromes neurológicos asociados con el consumo de plantas y hongos con componente tóxico. Rev Neurol 2003; 36: 860-871.
Lin CC, Chan TY, Deng JF. Clinical features and management of herb-induced aconitine poisoning. Ann Emerg Med 2004; 43: 574-579.
Al-Shaikh AM. Sablay hallucinogenic plant poisoning in children. Saudi Med L J 2005; 26: 118-121.