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2012, Number 4

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Rev Cubana Pediatr 2012; 84 (4)

Renal scintigraphy in children with first febrile urinary tract infection

Duarte PMC, Guillén DA, Martínez SM, Hernández RE

Language: Spanish
References: 18
Page:
PDF size: 82.43 Kb.


ABSTRACT

Introduction: the urinary tract infection is one of the most frequent bacterial infections in the childhood.
Objectives: to learn about the acute renal alterations in the first febrile urinary tract infection, and to relate them to the studied variables.
Methods: two hundred eleven children diagnosed as first febrile urinary tract infection patients were studied and performed Tc-DMSA renal scintigraphy in the acute phase of infection. The results were correlated to the duration and intensity of the fever before the diagnosis, to the acute phase reactants (hemogram, erythrosedimentation and reactive-C protein) and to the results of imaging studies (renal ultrasound and mictional uretrocystography).
Results: females prevailed and 82.4 % of patients were under one year-old. In the study group, 54 % presented with scintigraphic alterations and the hypocapture pattern of the radiopharmaceutical was the predominant finding in 70 % of patients. There was significant association between the duration and intensity of the fever, and the renal alterations. Regarding the lab parameters, leukocytosis above 15 000, accelerated erythrosedimentation and raised reactive-C protein were statistically significant and related to the renal alterations, whereas the radiological findings observed in renal ultrasound and mictional urethrocystography were statistically correlated to the renal lesion detected in the scintigraphy.
Conclusions: high percentage of patients suffered the spread of infection over the renal parenchyma; additionally the studied clinical, lab and imaging variables indicated renal injure.


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