medigraphic.com

2004, Number 4

<< Back Next >>

Rev Med Hosp Gen Mex 2004; 67 (4)

Hyperkeratosis of the nipple and/or areola. A report of two cases and a review of the literature

Mercadillo PP, Sandoval NJ, García RV, Peniche RJ

Language: Spanish
References: 16
Page: 203-207
PDF size: 124.93 Kb.


ABSTRACT

Hyperkeratosis of the areola and/or nipple (HAN), is a rare and benign dermatoses, with unknown origin, characterized for persistent verrucous thickening and hyperpigmentation of the areola, nipple or both. It is usually an asymptomatic lesion, it does not interfere with breast function, but has a psychologic impact in the patient. Today there are three classification; the first was postulated by Levy-Frankel in 1938, the second by Pérez-Izquierdo et al, 1990 and third Mehanna et al, 2001, with possible common background in etiology. Specific treatment does not exist, partly because of the unknown pathogenesis of this disorder. We report two cases, a 62 year-old woman with idiopathic hyperkeratosis of the areola and a 50 year-old man with secondary hyperkeratosis of the areola, both patients were treated with shave excision.


REFERENCES

  1. Krishnan RS, Angel TA, Roark TR, Hsu S. Nevoid hyperkeratosis of the nipple and/or areola: a report of two cases and a review of the literature. Int J Dermatol 2002; 41: 775-777.

  2. Baykal C, Buyukbabani N, Kavak A, Alper M. Nevoid hyperkeratosis of the nipple and areola: A distinct entity. J Am Acad Dermatol 2002; 46: 414-418.

  3. Revert A, Bañuls J, Montesinos E, Jorda E, Ramon D, Torres V. Nevoid hyperkeratosis of the areola. Int J Dermatol 1993; 32: 745-746.

  4. Schwartz RA. Hyperkeratosis of nipple and areola. Arch Dermatol 1978; 114: 1844-1845.

  5. Kuhlman DS, Hodge SJ, Owen LG. Hyperkeratosis of the nipple and areola. J Am Acad Dermatol 1985; 13: 596-598.

  6. Ferrando J, Navarra E, Torres MJ. Neviform hyperkeratosis of the mammary areola. Med Cutan Ibero Lat Am 1981; 9: 285-288.

  7. Allegue F, Soria C, Rocamora A, Fraile G, Ledo A. Hyperkeratosis of the nipple and areola in a patient with cutaneous T-cell lymphoma. Int J Dermatol 1990; 29: 519-520.

  8. Ahn SK, Chung J, Soo-Lee W, Kim SC, Lee SH. Hyperkeratosis of the nipple and areola simultaneously developing with cutaneous T-cell lymphoma. J Am Acad Dermatol 1995; 32: 124-125.

  9. Mehanna A, Malak JA, Kibbi AG. Hyperkeratosis of the nipple and areola: Report of 3 cases. Arch Dermatol 2001; 137: 1327-1328.

  10. Kubota Y, Koga T, Nakayama J, Kiryu H. Nevoid hyperkeratosis of the nipple and areola in a man. Br J Dermatol 2000; 142: 382-384.

  11. Perez-Izquierdo JM, Vilata JJ, Sanchez JL, Gargallo E, Millan F, Aliaga A. Retinoic acid treatment of nipple hyperkeratosis. Arch Dermatol 1990; 126: 687-688.

  12. Xifra M, Lagodin C, Wright D, Abbruzzese M, Woscoff A. Nevoid keratosis of the nipple. J Am Acad Dermatol 1999; 41: 325-326.

  13. Busse A, Peschen M, Schopf E, Vanscheidt W. Treatment of hyperkeratosis areolae mammae naeviformis with the carbon dioxide laser. J Am Acad Dermatol 1999; 41: 274-276.

  14. Vestey JP, Bunney MH. Unilateral hyperkeratosis of the nipple: the response to cryotherapy. Arch Dermatol 1986; 122: 1360-1361.

  15. Mayock P. Hyperkeratosis of the nipples. Arch Dermatol 1978; 114: 1245.

  16. Bayramgürler D, Bilen N, Apaydin R, Ercin C. Nevoid hyperkeratosis of the nipple and areola: treatment of two patients with topical calcipotriol. J Am Acad Dermatol 2002; 46: 131.




2020     |     www.medigraphic.com