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2012, Number 4

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Rev Cubana Plant Med 2012; 17 (4)

Effect of extracts from Anethum graveolens, Melissa officinalis y Calendula officinalis on the human spermatozoa

Puerta SJ, Cardona DD, Álvarez GA, Arango V, Cadavid A, Cardona MW

Language: Spanish
References: 32
Page: 420-430
PDF size: 253.51 Kb.


ABSTRACT

Introduction: there is wide availability of contraceptives; however unwanted pregnancy rate is not decreasing. One of the contraceptive methods employed are spermicides.
Objective: the objective of this study was to evaluate the effect of extracts from three plants extract: Anethum graveolens L. (Apiaceae), Calendula officinalis L. (Asteraceae), and Melissa officinalis L. (Lamiaceae) on the motility and viability of the human spermatozoon.
Methods: semen samples from healthy volunteers were incubated with each plant extract at different concentrations, and the effects on spermatozoon motility and viability were evaluated.
Results: Anethum graveolens extract reduced motility and viability by 65.3 and 16 % (p< 0.05, 5 min vs. control), respectively; Melissa officinalis extract decreased motility by 78.2 % and viability by 22.3 % (p< 0.05, 5 min vs. control). Finally, Calendula officinalis extract reduced motility and viability by 55.3 and 48.4 %, respectively (p< 0.05, 5 min vs. control).
Conclusions: none of the plant extracts at concentrations used in this assay has spermicidal effect on human sperm.


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