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Anales de Otorrinolaringología Mexicana

2012, Number 4

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Otorrinolaringología 2012; 57 (4)

Reversible neurosensorial hearing loss related to aspirin overdose in a patient with osteogenesis imperfecta

Morales OC, Gutiérrez SG, Fernández EJ, Yance VM

Language: Spanish
References: 38
Page: 230-235
PDF size: 271.40 Kb.


ABSTRACT

Hearing loss and tinnitus are well-known secondary effects of acetyl salicylic acid. Tinnitus intensity and hearing loss grade are directly dose and time administration drug dependent. Hypoacusia prognosis and reversible tinnitus effects correlate with suppression, patient intrinsic factors and opportune treatment. The different mechanisms of aspirin through the whole auditory pathway affect outer hair cells, spiral ganglion, inferior colliculus and auditory cortex. This paper reports the case of a 15-year-old female patient with acute aspirin intoxication and superficial right neurosensorial hearing loss and bilateral tinnitus. Hypocusia was documented in auditory tests, electrical evoked otoacustic emissions were performed and patient was treated with prednisone. She showed a complete recovery of both symptoms after two weeks of treatment even subjacent diagnosis of osteogenesis imperfecta.


REFERENCES

  1. Cazals Y. Auditory sensori-neural alterations induced by salicylate. Prog Neurobiol 2000;62:583-631.

  2. Vane JR, Botting RM. The mechanism of action of aspirin. Thromb Res 2003;110(5-6):255-258.

  3. Anchung D, Jianzhong L, Wei S. Temporal processing in inferior colliculus and auditory cortex affected by high dose of salicylate. Brain Research 2010;1344:96-103.

  4. Mitchell JA, Akarasereenont P, Thiemermann C, Flower J, Vane JR. Selectivity of nonesteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase. Proc Natl Acad Sci USA 1993;90:11693-11697.

  5. Dieler R, Shehata-Dieler WE, Brownell WE. Concomitant salicylate-induced alterations of outer hair cell subsurface cisternae and electromotility. J Neurocytol 1991;20:637-653.

  6. Tunstall MJ, Gale JE, Ashmore JF. Action of salicylate on membrane capacitance of outer hair cells from the guinea-pig cochlea. Acta Otolaryngol 1991;111:707-718.

  7. Kakehata S, Santos-Sacchi J. Effects of salicylate and lanthanides on outer hair cell motility and associated gating charge. J Neurosci 1996;16:4481-4489.

  8. Fujimura K, Yoshida M, Goto K, Mori T, Suzuki H. Effect of salicylate on electrically evoked otoacustic emissions elicited in the first and third turns of the guinea pig cochlea. Acta Otolaryngol 2004;124:896-901.

  9. Moller AR. Pathophysiology of tinnitus. Ann Otol Rhinol Laryngol 1984;93:39-44.

  10. Eggermont JJ. Tinnitus: some thoughts about its origin. J Laryngol Otol Suppl 1984;9:31-37.

  11. Nam BH, Kim PS, Park YS, Worrell LA, et al. Effect of corticosteroid on salicylate-induced morphological changes of isolated cochlear outer hair cells. Ann Otol Rhinol Laryngol 2004;113:734-737.

  12. Olesen J. Calcium entry blockers in the treatment of vertigo. Ann NY Acad Sci 1988;522:690-697.

  13. Jastreboff PJ, Brennan JF. Special effects of nimodipine on the auditory system. Ann N Y Acad Sci 1988;522:716-718.

  14. Lassen LF, Hirsch BE, Kamerer DB. Use of nimodipine in the medical treatment of Meniere’s disease: clinical experience. Am J Otol 1996;17:577-580.

  15. Swinnen FK, Coucke PJ, De Paepe AM, et al. Osteogenesis imperfecta: the audiological phenotype lacks correlation with the genotype. Orphanet J Rare Dis 2011;6:88.

  16. Ochi K, Kinoshita H, Nishino H, Kenmochi M, Ohashi T. Effects of nimodipine on salycilate ototoxicity. Am Otol Rhinol Laryngol 2002;111:1092-1096.

  17. Sillence DO, Senn A, Danks DM. Genetic heterogeneity in osteogenesis imperfecta. J Med Genet 1979;16:101-116.

  18. Bosch J, López R, Gutiérrez G, Esteves A. Cirugía estapedial en la osteogénesis imperfecta. Acta Otorrinolaring Esp 1994;(Suppl 1):82-85.

  19. Leroux H. Decouverte de saliciline. J Chem Med 1830;6:341.

  20. Müller G. Beitrag zur Wirkung des salicylsauren Natrons beim Diabetes Mellitus. Berl Klin Wochenschr 1877;14:29-31.

  21. Gerhardt CF. Recherches sur les acides organiques anhydres. Ann Chim Phys 1853;37:285-342.

  22. Schacht J, Hawkins JE. Sketches of Otohistory. Audiol Neurotol 2006;11:1-6.

  23. Falbe-Hansen J. Clinical and experimental histological studies of the effects of salicylates and quinine on the ear. Acta Otolaryngol 1941;Suppl 44:1-216.

  24. Jager BV, Alway R. The treatment of acute rheumatic fever with large doses of sodium salicylate. Am J Med Sci 1946;211:273-285.

  25. Graham JD, Parker WA. The toxic manifestations of sodium salicylate therapy. Quart J Med 1948;17:153-163.

  26. Weiss JF, Lever WF. Percutaneous salicylic acid intoxication in psoriasis. Arch Dermatol 1964;90:614-619.

  27. Myers EN, Bernstein JM. Salicylte ototoxicity; a clinical and experimental study. Arch Otolaryngol 1965;82:483-493.

  28. McCabe PA, Dey FL. The effect of aspirin upon auditory sensivity. Ann Otol Rhinol Laryngol 1965;74:312-324.

  29. Perlman LV. Salicylate intoxication from skin application. N Engl J Med 1966;274:164.

  30. Bernstein JM, Weiss AD. Further observations on salicylate ototoxicity. J Laryngol Otol 1967;81:915-925.

  31. Hicks ML, Bacon SP. Effects of aspirin on psychophysical measures of frequency selectivity, two-tone suppression, and growth of masking. J Acoust Soc Am 1999;106:1436-1451.

  32. Mantz JM, Haegy JM, Tempe JD, Jaeger A. Acute aspirin poisoning in adults. Rev Prat 1978;28:4557-4562.

  33. Outdot J, Pignat JC, Martin H. Intoxication aigue à l’aspirine et surdité. A propos de 10 cas. J Fr Otorhinolaryngol Audiophonol Chir Maxillofac 1979;28:687-693.

  34. Gignoux M, Martin H, Cajgfinger H. Troubles cóchleo vestibulaires après tentative de suicide à l’aspirine. J Fr Otorhinolaryngol Chir Maxillofac 1966;15,631-635.

  35. Ramsden RT, Latif A, O’Malley S. Electrocochleographic changes in acute salicylate overdosage. J Laryngol Otol 1985;99:1269-1273.

  36. Janssen T, Boege P, Oestreicher E, Arnold W. Tinnitus and 2f1-f2 distortion product otoacoustic emissions following salicylate overdose. J Acoustic Soc Am 2000;107(3);1790-1792.

  37. Kapur YP. Ototoxicity of acetylsalicylic acid. Arch Otolaryngol 1965;81:134-138.

  38. Jarvis JF. A case of unilateral permanent deafness following acetylsalicylic acid. J Laryngol Otol 1966;80:318-320.




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