2004, Number 1
<< Back Next >>
Rev Med Hosp Gen Mex 2004; 67 (1)
Experimental model of power-time-damage correlation of the radiofrequency effects
Mendieta-Alcántara GG, Mendieta-Zerón H
Language: Spanish
References: 13
Page: 7-10
PDF size: 86.71 Kb.
ABSTRACT
Introduction: Radiofrequency is the first choice therapeutic option to treat specific arrhythmias.
Objective: To demonstrate that radiofrequency can produce limited damage and to determine the correlation among power, time and the damaged area.
Methods: Prospective, experimental study. Twenty two dogs were divided into two groups. The right femoral vein was dissected to introduce an electrocatheter, placing it in the right atrium. With digital control it was emitted a discharge with power and time previously chosen. The necrotic area was measured microscopically. The statistical analysis was made with the parabolic model.
Results: In the parabolic model with constant time, the standard error was of 0.3750.
Conclusions: The results confirms that the lesions produced by radiofrequency are limited, and predictible, and suggests that the lesioned area appears to correlate better with the power in the parabolic model.
REFERENCES
Zipes DP, DiMarco JP, Gillette PC, Jackman WM, Myerburg RJ, Rahimtoola SH et al. Guidelines for clinical intracardiac electrophysiological ad catheter ablation procedures. A report of th American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Clinical Intracardiac Electrophysiologic an Catheter Ablation Procedures), developed in collaboration with the North American Society of Pacig and Electrophysiology. J Am Col Cardiol 1995; 26 (2): 555-573.
Nakagawa H, Wittkampf FH, Yamanashi WS, Pitha JV, Imai S, Campbell B et al. Inverse relationship between electrode size and lesion size during radiofrequency ablation with active electrode cooling. Circulation 1998; 98 (5): 458-465.
Miles WM, Klein LS, Hackett FK. Catheter ablation for cardiac arrhythmias. Cur Op Cardiol 1993; 8 (1): 75-87.
Nacarelli GV, Kuck KH, Pitha J, Carmen L, Jackman WM. Selective catheter ablation of canine ventricular myocardium with radiofrequency current. ACC 1987; 9 (2): 99-A.
Petersen HH, Chen X, Pietersen A, Svendsen JH, Haunso S. Lesion size in relation to ablation site during radiofrequency ablation. Pac Clin Electrophysiol 1998; 21 (1, pt 2): 322-326.
Avitall B, Mughal K, Hare J, Helms R, Krum D. The effects of electrode tissue contact on radiofrequency lesion generation. Pac Clin Electrophysiol 1997; 20 (12, pt 1): 2899-2910.
Otomo K, Yamanashi WS, Tondo C, Antz M, Bussey J, Pitha JV et al. Why a large tip electrode makes a deeper radiofrequency lesion: Effects of increase in electrode cooling and electrode tissue interface area. J Cardiovas Electrophysiol 1998; 9 (1): 47-54.
Haverkamp W, Hindricks G, Gulker H, Rissel U, Pfennings W, Borggrefe M, Breithardt G. Coagulation of ventricular myocardium using radiofrequency alternating current: bio-physical aspects and experimental findings. Pac Clin Electrophysiol 1989; 12 (1, pt 2): 187-195.
Wittkampf F, Hauer R, Robles de Medina E. Control of radiofrequency lesion size by power regulation. Circulation 1989; 80 (4): 962-968.
Iturralde TP, Colín LL, Guevara VM, Rodríguez CL, Kershenovich SS. Experiencia en 1,500 pacientes sometidos a ablación con radiofrecuencia en el tratamiento de las taquicardias. Arch Inst Cardiol Mex 2000; 70: 349-366.
Jackman WM, Kuch KH, Naccarelli GV, Carmen L, Pitha J. Radiofrequency current directed across the mitral anulus with a bipolar epicardial-endocardial catheter electrode configuration in dogs. Circulation 1988; 78 (5, pt 1): 1288-1298.
Ko WC, Huang SK, Lin JL, Shau WY, Lai LP, Chen PH. New method for predicting efficiency of heating by measuring bioimpedance during radiofrequency catheter ablation in humans. J Cardiovasc Electrophysiol 2001; 12 (7): 819-823.
Anfinsen OG, Kongsgaard E, Foerster A, Aass H, Amlie JP. Radiofrequency current ablation of porcine right atrium: increased lesion size with bipolar two catheter technique compared to unipolar application in vitro and in vivo. Pac Clin Electrophysiol 1998; 21: 69-78.