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Instituto Nacional de Neurología y Neurocirugía

2012, Number 2

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Arch Neurocien 2012; 17 (2)

Emotional modulation of memory: neurobiological findings

Solís-Vivanco R

Language: Spanish
References: 123
Page: 119-128
PDF size: 87.69 Kb.


ABSTRACT

In the last decades Neuroscience research has confirmed that we are able to remember better those events that were associated to an emotion, specially stress. The aim of this work was to review the more relevant neurobiological findings related to the emotional modulation of memory. The amygdala, specifically the basolateral nucleus, has a determining participation in emotional/stressful events consolidation; stress hormones, noradrenaline and glucocortidoids are also reported. This enhancement, demonstrated in animal studies and neuropsychological human research, has been observed in information consolidation and recall for declarative memory, as well as in the classic conditioning for non-declarative memory, and it is mediated by functional and morphological changes in the amygdala and other related brain regions, specially the hippocampus. The relevance of knowledge about neurobiological bases of this enhancement effect is concluded due to its implications for psychiatric disorders related to stress.


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