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2012, Number 2

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Revista del Hospital Psiquiátrico de La Habana 2012; 9 (2)

Chromosomal Aberrations and Schizophrenia

Morales RE

Language: Spanish
References: 77
Page:
PDF size: 227.76 Kb.


ABSTRACT

Schizophrenia is a mental disorder affecting world population, with a prevalence of 1 % and inheritability to 80 %. Studies of genetic linkage, genomic convergence, and of chromosome association and aberrations, have contributed to susceptibility gene identification and to establish molecular markers associated to schizophrenia. With this review, knowledge about the antecedents has possibly been extended to the valid classification, epidemiology and diagnosis of the disease, and to emphasize in chromosomal aberrations reported in patients with schizophrenia as a part of the genetic factors found in this pathology. Several published and archived articles in scientific databases were consulted, thus enabling us to obtain a close approach to the estimation of the frequency of these findings, and allowing to continue evaluating the possible association of Schizophrenia with chromosome aberrations.


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