Luna-López A, López- Diazguerrero NE, González-Puertos VY, Triana-Martínez F, Königsberg FM

Language: Spanish
References: 25
Page: 93-102
PDF size: 221.35 Kb.

ABSTRACT

Bcl-2 is a protein that has traditionally been related to programmed cell death or apoptosis prevention. However, in the last years other physiological functions for this protein have been described, such as oxidative stress damage prevention, calcium homeostasis preservation and cell cycle regulation, all these suggests that Bcl-2 is a molecule involved in cell survival. In this paper some functions of Bcl-2 will be described, as well as the Bcl-2 promoter and some mechanisms that regulate Bcl-2 expression.

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