Padilla-Rodríguez AL, Hernández-González M, Alcántara-Vázquez A

Language: Spanish
References: 14
Page: 29-32
PDF size: 136.82 Kb.

ABSTRACT

We present the case of a 45 year-old woman with a tumor completely removed from the left major lip of the vulva. The tumor was 4 x 4 x 3.5 cm., with very well defined edges. It was covered by surrounding skin and showed a white to yellow color with a myxoid appearance. The histopathological study showed a very well defined tumor composed of edematous loose connective tissue with hipo-and hipercellular areas of fusiform to plasmacitoid stromal cells; these cells showed benign characteristics. They were randomly distributed between wavy collagen fibers with abundant thin walled blood vessels; some of them showing perivascular irregular stromal cells. Immunohistochemistry showing the stromal cells to be positive for vimentin. All these findings are consistent with the diagnosis of angiomyofibroblastoma. The angiomyofibroblastoma is a low frequency with a benign course. It is mainly located in the vulva, and does not recur nor metastatize after resection. Among others the aggressive angiomyxoma is the main differential diagnosis; the latter has the capability to recur and requires wide border resections therefore the correct differentiation is important to establish a prognosis and the correct treatment.

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