1999, Number 3
Angioimmunoblastic lymphadenopathy. Physiopathology, cytogenetic, histology and treatment
Frenk P, Ylgovsky L
Language: Spanish
References: 33
Page: 132-137
PDF size: 144.51 Kb.
ABSTRACT
Immunoblastic lymphadenopathy, although it resembles Hodgkin’s disease, is a distinct hyperimmune disorder apparently of the B-cell system. It’s a disorder characterized by a sudden onset of constitutional symptoms and lymphadenopathy. Diagnosis requires a lymph node biopsy that shows architectural effacement, absence of germinal centers, arborization of post capillary venules, and a polymorphous infiltrate that includes immunoblasts. Laboratory features include autoimmune hemolytic anemia and polyclonal hypergammaglobulinemia.REFERENCES
Lorenzen J, Li G, Zhao HM, Wintzeer C, Fischer R, Hansmann ML. Angioimmunoblastic lymphadenopathy type of T-cell lymphoma and angioimmunoblastic lymphadenopathy: A clinicopathological and molecular biological study of 13 Chinese patients using polymerase chain reaction and paraffin-embedded tissues. Virchows-Arch 1994; 424: 593-600.