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Colegio de Medicos y Cirujanos República de Costa Rica

2012, Number 603

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Rev Med Cos Cen 2012; 69 (603)

Resección laparoscópica de tumor del estroma gastrointestinal (GIST)

Clachar HG, Araque AB, Arce CKM, Esmeral MJ

Language: Spanish
References: 15
Page: 423-429
PDF size: 229.86 Kb.


ABSTRACT

Gastrointestinal stromal tumors (GIST) are the most frequent mesenchymal tumors in the gastrointestinal tract. They originate from the interstitial cells of Cajal and are characterized by an anomalous receptor for a growth factor with tyrosine-kinase activity (ckit), are a heterogeneous group of tumors that express CD 117. They may behave as benign tumors or be highly aggressive. A better survival of patients with these tumors has been achieved using the new molecular therapies such as imatinib mesylate, sunitinib and others. This review analyzes the prognostic factors of these tumors, their clinical features and the criteria for malignant behavior. The valué of therapeutic alternatives such as the Laparoscopic Surgery Resection.


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