2012, Number 4
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Rev Mex Med Repro 2012; 4.5 (4)
Relation of sex hormones and bone mineral density with adipose tissue in men
Villarreal AJÁ, Díaz DEP, Basurto AL, Saucedo GR, Vega GS, Córdova PN, Campos LS, Vázquez AL, Rocha A, Hernández VM, Zárate TA
Language: Spanish
References: 20
Page: 159-163
PDF size: 82.43 Kb.
ABSTRACT
Objective: To determine the relationship among serum sex hormone levels (estradiol and testosterone), body mass index (BMI), and bone mineral density (BMD) in elderly men.
Patients and methods: Cross-sectional study was done including 105 men without associated diseases, aged 55 years and over. Height, weight and BMI were obtained; estradiol and testosterone levels were estimated by radioimmunoassay. BMD at lumbar spine and femoral neck was measured using dual energy X-ray absorptiometry.
Results: According to WHO criteria, 47.5% of participants had normal BMD, 40.1%, osteopenia and 12.4%, osteoporosis; 50.4% of participants had normal weight and the rest, overweight and obesity. Patients with osteopenia and osteoporosis had a lower BMI compared to participants with normal BMD. BMD was associated with estradiol levels (
r = 0.262,
p ‹ 0.001) and with BMI (
r = 0.341,
p/i> = 0.007).
Conclusion: The results indicate that patients with osteoporosis and osteopenia have a lower BMI and reduced concentrations of estradiol compared to health subjects. This suggests the importance of adipose tissue in the aromatization of androgens into estrogens, hormones that are essential in bone metabolism.
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