2012, Number 4
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Rev Mex Med Repro 2012; 4.5 (4)
Metformine administration in policystic ovary syndrome
Mateo SHA, Mateo SE, Hernández AL, Salazar REL
Language: Spanish
References: 12
Page: 141-146
PDF size: 93.70 Kb.
ABSTRACT
Statistics shows that polycystic ovary syndrome is a common syndrome affecting approximately 5-10% of women. Polycystic ovary syndrome (PCOS) is usually emotionally and physically exhausting for the women suffering it. Their desire to lose weight, continually making an effort, and finally not achieving it produce frustration and deception; on the other hand, the esthetic aspect worries women frequently, due to the excessive hair growth and acne. Ultimately, it is important to mention the fertility impact, which is one of the main medical consultation causes by PCOS. Treating the syndrome is not impossible, but it does have its complications due to the multiple factors that produce it. Studies show that hyperinsulinemia is the leading cause of most of biochemical alterations, so if they are treated a benefic effect is obtained. Metformin is the most used and studied antihyperglucemic drug in the market. Its impact on the physiopathology of the disease is overwhelming, improving androgen pathological biosynthesis, and therefore, improving ovarian functioning, which favors fertility.
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