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2011, Number 1

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Rev Hematol Mex 2011; 12 (1)

MicroRNA: biogenesis, functions and objetives identification

Vázquez GE

Language: Spanish
References: 100
Page: 39-46
PDF size: 103.34 Kb.


ABSTRACT

MicroRNAs are non-coding 20-30 nucleotide single stranded RNA molecules that are capable of regulating gene expression in eukaryotic organisms. Several studies have shown the involvement of miRNAs in cancer by a variety of mechanisms such as amplification, deletion, mutations and epigenetic factors. This review outline their importance, differences and validation mechanisms.


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