2012, Number 2
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Med Cutan Iber Lat Am 2012; 40 (2)
Kaposi’s sarcoma
Hernández-Ruiz E, García-Herrera A, Ferrando J
Language: Spanish
References: 19
Page: 39-48
PDF size: 138.02 Kb.
ABSTRACT
Kaposi´s sarcoma is a proliferative disease of lymphatic endothelial cells. There are four main clinical types: classical, endemic or African, epidemic or AIDS related and yatrogenic. Diagnosis is based on histopathological findings, but immunochemistry can help in some difficult cases or initial lesions. There are multiple choices of treatment but the most important ones are surgery, radiotherapy and chemotherapy. Most cases are indolent so treatments are used to avoid disease progression and relieve symptoms. Yatrogenic and AIDS related Kaposi´s sarcoma can be more aggressive with visceral involvement and require systemic therapies. There isn´t a stadiation scale or therapeutic guidelines, so there is a need of consensus in the following and treatment of these patients.
REFERENCES
Szajerka T, Jablecki J. Kaposi´s sarcoma revisited. AIDS Rev 2007; 9: 230-6.
Eng W, Cockerell CJ. Histological features of Kaposi sarcoma in a patient receiving highly active antiviral therapy. Am J Dermatopathol 2004; 26: 127-32.
Stribling J, Weitzner S, Smith GV. Kaposi’s sarcoma in renal allograft recipients. Cancer 1978 ;42: 442-6.
Requena L, Requena C. Histopathology of the more common viral skin infections. Actas Dermosifiliogr 2010; 101: 201-16.
Grayson W, Pantanowitz L. Histological variants of cutaneous Kaposi sarcoma. Diagnostic Pathol 2008; 3: 31.
Schwartz RA, Spicer MS, Janniger CK, Cohen PJ, Melczer MM, Lambert WC Keloidal Kaposi‘s sarcoma: report of three patients. Dermatology 1994; 189: 271-4.
Kempf W, Cathomas G, Burg G, Trüeb RM. Micronodular Kaposi’s sarcoma - a new variant of classic-sporadic Kaposi‘s sarcoma. Dermatology 2004; 208: 255-8.
Wyatt ME, Finlayson CJ, Moore-Gillon V. Kaposi’s sarcoma masquerading as pyogenic granuloma of the nasal mucosa. J Laryngol Otol 1998; 112: 280-2.
Schwartz RA, Spicer MS, Thomas I, Janniger CK, Lambert WC. Ecchymotic Kaposi’s sarcoma. Cutis 1995; 56: 104-6.
Luzar B, Antony F, Ramdial PK, Calonje E. Intravascular Kaposi’s sarcoma - a hitherto unrecognized phenomenon. J Cutan Pathol 2007; 34: 861-4.
Pantanowitz L, Dezube BJ. Kaposi sarcoma in inusual locations. BMC Cancer 2008; 8: 190.
Gambús G, Bourboulia D, Esteve A, Lahoz R, Rodríguez C, Bolao F et al. Prevalence and distribution of HHV-8 in different subpopulations, with and without HIV infection, in Spain. AIDS 2001; 15: 1167-74.
Emond JP, Marcelin AG, Dorent R, Milliancourt C, Dupin N, Frances C et al. Kaposi’s sarcoma associated with previous human herpesvirus 8 infection in heart transplant recipients. J Clin Microbiol 2002; 40: 2217-9.
Gutiérrez-Dalmau A, Sánchez-Fructuoso A, Sanz-Guajardo A, Mazuecos A, Franco A, Rial MC et al. Efficacy of conversion to sirolimus in posttransplantation Kaposi’s sarcoma. Transplant Proc 2005; 37: 3836-8.
Toyohama T, Nagasaki A, Miyagi J, Takamine W, Sunagawa K, Uezato H et al. Kaposi‘s sarcoma in a human immunodeficiency virus-negative patient treated with corticosteroid for idiopathic thrombocytopenic purpura. Intern Med 2003; 42: 448-9.
Piselli P, Busnach G, Citterio F, Frigerio M, Arbustini E, Burra P et al. Risk of Kaposi sarcoma after solid-organ transplantation: multicenter study in 4,767 recipients in Italy, 1970-2006. Transplant Proc 2009; 41: 1227-30.
Toschi E, Sgadari C, Monini P, Barillari G, Bacigalupo I, Palladino C et al. Treatment of Kaposi´s sarcoma: an update. Anti-Cancer Drugs 2002; 13: 977-87.
Campistol JM, Gutiérrez-Dalmau A, Torregrossa JV. Conversion to sirolimus: a successful treatment for posttransplantation Kaposi’s sarcoma. Transplantation 2004; 77: 760-2.
Cianfrocca M, Lee S, Von Roenn J, Tulpule A, Dezube B, Aboulafia D et al. Randomized trial of paclitaxel versus pegylated liposomal doxorubicina for advanced human immunodeficiency virus-associated Kaposi’s Sarcoma: Evidence for symptom palliation from chemotherapy. Cancer 2010; 116: 3969-77.