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ISSN 1561-3011 (Electronic)

2012, Number 2

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Rev Cubana Invest Bioméd 2012; 31 (2)

Risk factors and cardiovascular complications in patients with chronic renal disease on hemodialysis: prevalence, morbidity and mortality

Atiés SMC, Collado NS, Pascual SJ, Cao H, Barbosa F

Language: Spanish
References: 38
Page: 214-225
PDF size: 84.29 Kb.


ABSTRACT

Objectives: Describe cardiovascular risk factors (CVRF) and their association with cardiovascular disease (CVD) in patients with chronic renal disease (CRD) on hemodialysis (HD). Methods: A descriptive cross-sectional study was conducted with 345 prevalent adult patients of both sexes, aged 18 and over, following a conventional HD program irrespective of etiology at Mar de Barcelona Hospital and 3 other dialysis centers for which the said hospital is a reference center. All patients gave their informed consent in writing. A review was made of the medical records contained in databases at the said centers, and descriptive statistics were applied. Results: Mean age was 69.19±14.03; 71.5 % of patients were male; mean treatment time was 62.26±84.79 months. The frequency of classical CVRFs was the following: hypertension (82.5 %), diabetes mellitus (DM, 32.2 %), male sex (71.6 %) and dyslipemia (55.7 %). CVD was present in 60.5% of patients; 53.9 % was of cardiac origin proper. The following risk factors were associated with cardiovascular disease: smoking, dyslipidemia, DM, arterial hypertension (AHT), LVH, age, and Charlson comorbidity index, with a statistical significance of (p‹0.05). Conclusions: Patients with chronic renal disease on hemodialysis have a high frequency of CVD and classical CVRFs. The factors predicting clinical CVD in our population were age, the presence of subclinical CVD, LVH, and classical CVRFs (AHT, DM, dyslipidemia, smoking, age and Charlson comorbidity index).


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