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ISSN 0185-3252 (Print)
Revista de la Asociación Médica del Centro Médico ABC

2012, Number 1

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An Med Asoc Med Hosp ABC 2012; 57 (1)

Phrenic nerve electrical stimulation in prolonged mechanical ventilation patients

Flores MSM, Arch TE, Collado CMÁ, Shkurovich BP

Language: Spanish
References: 18
Page: 32-38
PDF size: 84.82 Kb.


ABSTRACT

Introduction: Phrenic nerve conduction studies represent a non-invasive, safe and reproducible technique in intubated patients receiving mechanical ventilation. Material and methods: In this study we performed electrical stimulation of the phrenic nerve in five intubated patients receiving mechanical ventilation and compared muscle action potentials of the diaphragm muscle and phrenic nerve neuroconduction, with a control group using Student’s «t» test and Pearson correlation analysis. Results: Phrenic nerve electrical stimulation was possible to perform in all intubated patients receiving mechanical ventilation as well as in the control group subjects. The study group showed a statistically significant decrease in the muscle action potential compared with the control group (p = 0.002). There was a clear correlation of amplitude depression of the muscle action potential and the duration of mechanical ventilation in the Pearson analysis (r = -0.992). Conclusions: It is possible to perform non-invasive phrenic nerve conduction with electrical stimulation in patients receiving mechanical ventilation. Our study shows a progressive depression of the muscle action potential of the right phrenic nerve and eventual conduction failure as early as 80 hours after mechanical ventilation is started.


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