Morales CD, Jiménez FL

Language: Spanish
References: 10
Page: 199-204
PDF size: 166.21 Kb.

ABSTRACT

Intrahepatic cholestasis is the most common liver disease that occurs during pregnancy, was originally described in 1883 by Ahlfeld. It has a higher incidence during the third gestational trimester. One of its characteristics is the presence of a severe pruritus and alteration on the liver functions, it carries a moderate risk of preterm labor or still births, the symptoms disappear within days of delivery but it remains an important problem for the obstetric community. The cause of this pathology has not yet been determined but it has been associated with genetic, hormonal and even environmental factors. Treatment is based solely in diminishing the symptoms in patients and the use of ursodeoxicolic acid is the pharmacologic treatment proven more effective to date. This is based in the analysis of literature and clinical trials of such an important and not well unknown pathology. (4).

REFERENCES

1. Emmanouil Sinakos MD, Keith D. Lindor MD. , Bile Acid Proliles in Intrahepatic Cholestasis of Pregnancy: Is This the Solution to the Enigma of Intrahepatic Cholestasis of Pregnancy?. The American Journal of Gastroenterology. 2010. Pag. 596- 598.

2. Geenes V. , Williamson C. , Intrahepatic Cholestasis of pregnancy. World journal of gastroenterology. 2009. Pag 2049-2066.

3. Jurate Kondrackiene, Limas Kupcinskas. Intrahepatic Cholestasis of Pregnancy- Current Achievements and Unsolved Problems. World journal of Gastroenterology. 2008. Pag 5781- 5788.

4. Kandranckiene J. , Kupcinskas C. , Intrahepatic cholestasis of pregnancy- current achievements an unsolved problems. World journal of gastroenterology. 2008. Pag 5781-5788.

5. Leslie et al. Estrogens in intrahepatic cholestasis of pregnancy. Obstetric and gynecology 2000. Pag 372-376.

6. Mahmoud M. Saleh, Khalil R. Abdo. Intrahepatic Cholestasis of Pregnancy: Review of the literature and evaluation of current evidence. Journal of Women´s Heald, Volume 16, Number 6, 2007. Pag 833- 839.

7. Oztekin et al, Predicting fetal asphyxia in intrahepatic cholestasis of pregnancy. Obstetrical and ginecological survery 2009. Pag 975- 979.

8. Pusl T. , Beuers U. , Intrahepatic cholestasis of pregnancy. Orphanet journal of rare diseases, 2007.

9. Vannick B. , Intrahepatic cholestasis of pregnancy. Uptodate 2010.

10. Victoria Geenes, Catherine Williamson, Intrahepatic Cholestasis of Pregnancy. World journal of gastroenterology. 2009. Pag. 2049- 2066.