Guzmán-Juárez W, Ávila-Esparza M, Contreras-Solís RE, Levario-Carrillo M

Language: Spanish
References: 15
Page: 461-466
PDF size: 828.82 Kb.

ABSTRACT

Background: Hypertensive complications in pregnancy are a cause of morbidity and mortality. Previous studies have identified similarities and differences in risk factors of hypertensive complications during pregnancy.
Objective: Determine factors associated with gestational hypertension (HTG) and those related to preeclampsia (PEE).
Patients and methods: Case-control study. We included women who completed pregnancy without complications (n = 260) and were diagnosed with HTG (n = 65) and PEE (n = 65). We excluded patients with gestational or pre-pregnancy diabetes, thyroid disease (hypo and hyperthyroidism), autoimmune diseases (lupus erythematosus, rheumatoid arthritis) or diagnosed with heart disease or neuropathy before pregnancy.
Results: There were similarities in the risk factors such as: age over 35 years (OR 8.8, 95% CI 2.91-22.40), previous HTG (OR 64.16 95% CI 13.04-315.57) in case of patients with PEE. But we found a difference in the magnitude of these associations as odds ratios (OR) estimates were higher than in patients with HTG, age over 35 years (OR 3.33, 95% CI 1.03-10.72), and previous HTG (OR 27.27 95% CI 5.60-132.87). First-time pregnant women showed similar associations (OR 3.11 95% CI 1.52-6.38) in case of PEE or HTG (OR 3.14 95% CI 1.65-5.97).
Conclusion: There are similarities in risk factors: maternal age ≥ 35 years, previous gestational hypertension and first-time pregnancy, for the development of gestational hypertension and preeclampsia.

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