2012, Number 1
<< Back Next >>
Rev Cub Oftal 2012; 25 (1)
Regenerative medicine and ocular surface
Cárdenas DT, Capote CA, Benítez MMC, Noriega MJL, Montero DE, Hormigó PIF
Language: Spanish
References: 67
Page:
PDF size: 80.12 Kb.
ABSTRACT
In the last few years, an extraordinary advance has taken place in the knowledge about several biomedical branches as is the case of cellular biology, which has remarkably encouraged the development of a new medical branch called regenerative medicine. This medical discipline is fundamentally based on the new knowledge on the stem cells and their capacity to become cells for different tissues. One of the most interesting structures for the regenerative medicine is the ocular surface. In the last few years, significant advances have been achieved in the field of the ocular surface reconstruction with regenerative procedures. Some cell cultures of the human corneal epithelium are being used to treat limber insufficiency, to reduce the incidence of haze-type opacities after photorefractive keratectomy, to speed up the curing process and avoid the occurrence of leukomas in patients with persistent epitelial defects, and to decrease the incidence of corneal opacities in patients undergoing photorefractive keratectomy due to different corneal dystrophies.
REFERENCES
Mironow V, Visconti RP, Markwald RR. What is regenerative medicine? Emergence of applied stem cell and developmental biology. Expert Opin Biol Ther. 2004 [citado 2010 ene 15];4(6). Disponible en: http://informahealthcare.com/doi/abs/10.1517/14712598.4.6.773
Verfaillie CM, Pera MF, Lansdorp PM. Stem cells: Hype and reality. Hematology. 2002 [citado 2010 ene 15];2002(1). Disponible en: http://asheducationbook.hematologylibrary.org/content/2002/1/369.full.pdf+html
Hernández P, Dorticós E. Medicina regenerativa. Células madre embrionarias y adultas. Rev Cubana Hematol Inmunol Hemoter. 2004 [citado 2010 ene 15];20(3). Disponible en: http://www.sld.cu/sitios/medregenerativa/temas.php?idv=13084
Gavira JJ, Herreros J, Rábago G, Luquin R, Prósper F, Moreno J, et al. Trasplante celular y terapia regenerativa con células madre. Anales del Sistema Sanitario de Navarra. 2006 [citado 2010 ene 15];29(2). Disponible en: http://dialnet.unirioja.es/servlet/articulo?codigo=2116819
Potten CS, Loeffler M. Stem cells: attributes, cycles, spirals, pitfalls and uncertainties. Lessons for and fromthe crypt. Development. 1990 [citado 2010 ene 15];110(4). Disponible en: http://dev.biologists.org/content/110/4/1001.short
Dua HS, Azuara-Blanco A. Limbal stem cells of the corneal epithelium. Surv Ophthalmol. 2000 [citado 2010 ene 15];44(5). Disponible en: http://www.surveyophthalmol.com/article/S0039-6257(00)00109-0/abstract
García M, Echeveste J, Fernández A, Moreno J, Prósper F. Regeneración de la superficie ocular: stem cells/células madre y técnicas reconstructivas. An Sist Navar. 2008 [citado 2010 ene 15];31(1). Disponible en: http://en.scientificcommons.org/34574843
Weissman IL, Anderson DJ, Gage F. Stem and progenitor cells: origins, phenotypes, lineage commitments, and transdifferentiations. Annu Rev Cell Dev Biol. 2001 [citado 2010 ene 15];17. Disponible en: http://www.annualreviews.org/doi/abs/10.1146/annurev.cellbio.17.1.387
Hernández P. Medicina regenerativa II. Aplicaciones, realidad y perspectivas de la terapia celular. Rev Cubana Hematol Inmunol Hemoter. 2006 [citado 2010 ene 15];22(1). Disponible en: http://www.bvs.sld.cu/revistas/hih/vol22_1_06/hih02106.htm
Schermer A, Galvin S, Sun T. Differentiation-related expression of a major 64 K corneal Keratin in vivo and in culture suggests limbal location of corneal epithelial stem cells. J Cell Biol. 1986 [citado 2010 ene 15];103(1). Disponible en: http://jcb.rupress.org/content/103/1/49.abstract
Bohórquez Rodríguez P, Benítez del Castillo JM, Ragai N, Chen Y-T. Principios de biología molecular de la superficie ocular. Studium. 2000 [citado 2010 ene 15];18(2). Disponible en: http://www.oftalmo.com/studium/studium1999/stud99-2/99b01.htm
Tseng SCG. Concept and application of limbal stem cells. Eye. 1989 [citado 2010 ene 15];3. Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/2695347
Boulton M, Albon J. Stem cells in the eye. Int J Biochem Cell Biol. 2004 [citado 2010 ene 15];36(4). Disponible en: http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TCH-4B8K9BR-1&_user=10&_coverDate=04%2F30%2F2004&_rdoc=1&_fmt=high&_orig=gateway&_origin=gateway&_sort=d&_docanchor=&view=c&_searchStrId=1698387380&_rerunOrigin=scholar.google&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=c36a83213882755de2f2acdceb86d3b0&searchtype=a
Tseng SC, Tsubota K. Important concepts for treating ocular surface and tear disorders. Am J Ophthalmol. 1997 [citado 2010 ene 15];124(4). Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/9402829
Schultz GS. Modulation of corneal wound healing. En: Krachmer JH, Maunis MJ, Holland EJ, editores. Cornea. St Louis: Mosby; 1997. p. 183-98.
Kruse FE, Völcker HE. Stem cells, wound healing, growth factors and angiogenesis in the cornea. Current Opinion in Ophthalmol. 1997 [citado 2010 ene 15];8(4). Disponible en: http://journals.lww.com/co-ophthalmology/Abstract/1997/08000/Stem_cells,_wound_healing,_growth_factors,_and.7.aspx
Davanger M, Evensen A. Role of the pericorneal papillary structure in renewal of corneal epithelium. Nature. 1971 [citado 2010 ene 15];229(5286). Disponible en: http://www.nature.com/nature/journal/v229/n5286/abs/229560a0.html
Puangsricharern V, Tseng SCG. Cytologic evidence of corneal diseases with limbal stem cell deficiency. Ophthalmology. 1995 [citado 2010 ene 15];102(10). Disponible en: http://cat.inist.fr/?aModele=afficheN&cpsidt=3695452
Ellies P, Andersson DF, Topuhanmi A, Tseng SCG. Limbal stem cell deficiency arising from systemic chemotherapy. Br J Ophthalmol. 2001 [citado 2010 ene 15];85(3). Disponible en: http://bjo.bmj.com/content/85/3/371.4.extract
Toro A., Ruiz C, Castillón L. Trasplante de limbo corneal. En: Actualizaciones en Trasplantes. 2004 [citado 2010 ene 15]. Disponible en: http://www.sld.cu/galerias/pdf/sitios/trasplante/tejidos04-3.pdf
Sedó S, Torras J. La superficie ocular (2ª parte). Annals d´Oftalmologia. 2001 [citado 2010 ene 15];9(4). Disponible en: http://www.nexusediciones.com/pdf/ao2001_4/of-9-3-002.pdf
Tsubota K, Satake Y, Kaido M, Shinozaki N, Shimmura S, Bissen-Miyajima H, et al. Treatment of severe ocular surface disorders with corneal stem-cells transplantation. N Engl J Med. 1999 [citado 2010 ene 15];340(22). Disponible en: http://www.nejm.org/doi/pdf/10.1056/NEJM199906033402201
Anderson DF, Ellies P, Pires RTF, Tseng SCG. Amniotic membrane transplantation for partial limbal stem cell deficiency. Br J Ophthalmol. 2001 [citado 2010 ene 15];85(5). Disponible en: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1723950/pdf/v085p00567.pdf
Kenyon KR, Tseng SC. Limbal autograft transplantation for ocular surface disorders. Ophthalmology. 1989 [citado 2010 ene 15];96(5). Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/2748125
Dunaief J, Goldberg M. Corneal dystrophies of epithelial genesis. The possible therapeutic use of limbal stem cell transplantation. Arch Ophthalmol. 2001 [citado 2010 ene 15];119(1). Disponible en: http://archopht.ama-assn.org/cgi/content/short/119/1/120
Rodríguez MJ, Martín BF, Arteaga HV, Abreu RJ, Aguilar EJ, González De La RM. Transplante de Limbo en patología de la superficie ocular. Arch Soc Canar Oftal. 2003 [citado 2010 ene 15];(14). Disponible en: http://www.oftalmo.com/sco/revista-14/14sco12.htm
Tsubota K, Toda I, Saito H, Shinozaki N, Shimazaki J. Reconstruction of the corneal epithelium by limbal allograft transplantation for severe ocular surface disorders. Ophthalmology. 1995 [citado 2010 ene 15];35(4). Disponible en: http://journals.lww.com/internat-ophthalmology/Citation/1995/03540/Reconstruction_of_Corneal_Epithelium_by_Limbal.39.aspx
Tsai RJ, Li LM, Chen JK. Reconstruction of damaged corneas by transplantation of autologous limbalepithelial cells. N Engl J Med. 2000 [citado 2010 ene 15]; 343:86-93. Disponible en: http://www.nejm.org/doi/pdf/10.1056/NEJM200007133430202
Schwab IR, Reyes M, Isseroff RR. Successful transplantation of bioengineered tissue replacements inpatients with ocular surface disease. Cornea. 2000 [citado 2010 ene 15];19(4). Disponible en: http://journals.lww.com/corneajrnl/Abstract/2000/07000/Successful_Transplantation_of_Bioengineered_Tissue.3.aspx
Koizumi N, Inatomi T, Suzuki T, Sotozono C, Kinoshita S. Cultivated corneal epithelial stem celltransplantation in ocular surface disorders. Ophthalmology. 2001 [citado 2010 ene 15];108(9). Disponible en: http://cat.inist.fr/?aModele=afficheN&cpsidt=14077499
He YG, Alizadeh H, Kinoshita K, McCulley JP. Experimental transplantation of cultured human limbal andamniotic epithelial cells onto the corneal surface. Cornea. 1999 [citado 2010 ene 15];18(5). Disponible en: http://journals.lww.com/corneajrnl/Abstract/1999/09000/Experimental_Transplantation_of_Cultured_Human.10.aspx
Rama P, Bonini S, Lambiase A, Golisano O, Paterna P, De Luca M, et al. Autologous fibrin-cultured limbalstem cells permanently restore the corneal surface of patients with total limbal stem cell deficiency. Transplantation. 2001 [citado 2010 ene 15];72(9). Disponible en: http://journals.lww.com/transplantjournal/Abstract/2001/11150/Autologous_Fibrin_Cultured_Limbal_Stem_Cells.2.aspx
Koizumi N, Inatomi T, Suzuki T. Cultivated corneal epithelial transplantation for ocular surface reconstruction in acute phase of Stevens-Johnson syndrome. Arch Ophthalmol. 2001 [citado 2010 ene 15];119(2):298-300. Disponible en: http://archopht.ama-assn.org/cgi/content/full/119/2/298
Kim MK, Heo JW, Lee JL, Wee WR, Lee JH. Adhesion complex in cultivated limbal epithelium on amniotic membrane after in vivo transplantation. Curr Eye Res. 2005 [citado 2010 ene 15];30(8). Disponible en: http://informahealthcare.com/doi/abs/10.1080/02713680590968277
Ma DH, Yao JY, Yeh LK, Lian ST, See LC, Chen HT, et al. In vitro antiangiogenic activity in ex vivo expanded human limbocorneal epithelial cells cultivated on human amniotic membrane. Invest Ophthalmol Vis Sci. 2004 [citado 2010 ene 15];45(8). Disponible en: http://www.iovs.org/content/45/8/2586.short
Hayashida Y, Nishida K, Yamato M, Yang J, Sujiyama H, Watanabe K, et al. Transplantation of tissue-engineered epithelial cell sheets after Excimer laser photoablation reduces postoperative corneal haze. Invest Ophthalmol Vis Sci. 2006 [citado 2010 ene 15];47(2):552-7. Disponible en: http://www.iovs.org/content/47/2/552.short
McCanna DJ, Harrington KL, Driot JY, Ward KW, Tchao R. Use of a human corneal epithelial cell line for acreening the safety of contact lens care solutions in vitro. Eye Contact Lens. 2008 [citado 2010 ene 15];34(1). Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/18180675
Dutot M, Pouzaud F, Larosche I, Brinole-Baudouin F, Warnet JM, Rat P. Floroquinolone eye drop-induced cytotoxicity: role of preservative in P2X7 cell death receptor activation and apoptosis. Invest Ophthalmol Vis Sci. 2006 [citado 2010 ene 15];47(7). Disponible en: http://www.iovs.org/content/47/7/2812.short
Huhtala A, Pohjonen T, Salminen L, Salminen A, Kaarniranta H, Uusitalo H, et al. In Vitro biocompatibility of degradable biopolymers in cell line cultures from various ocular tissues: direct contact studies. J Biomed Mater Res. 2007 [citado 2010 ene 15];83(2):407-13. Disponible en: http://onlinelibrary.wiley.com/doi/10.1002/jbm.a.31319/abstract?systemMessage=Wiley+Online+Library+will+be+disrupted+2nd+Apr+from+10-12+BST+for+monthly+maintenance
Nishida K, Yamato M, Hayashida Y, Watanabe K, Yamamoto K, Adachi E, et al. Corneal reconstruction with tissue _ engineered cell sheets composed of autologous oral mucosa epithelium. N Engl J Med. 2004 [citado 2010 ene 15]; 351:1187-96. Disponible en: http://journal.shouxi.net/qikan/article.php?id=210047
Campos A. Cuerpo, Histología y Medicina. De la descripción microscópica a la Ingeniería Tisular. Discurso de Ingreso en la Real Academia Nacional de medicina. Madrid 2004 [citado 2010 ene 15]. Disponible en: http://books.google.com/books?hl=es&lr=&id=zJUqDieftIEC&oi=fnd&pg=PA7&dq=Cuerpo,+Fisiolog%C3%ADa+y+Medicina.+De+la+descripci%C3%B3n+microsc%C3%B3pica+a+la+Ingenier%C3%ADa+Tisular.+Discurso+de+Ingreso+en+la+Real+Academia+Nacional+de+medicina.&ots=dtUlBa2Vll&sig=zeSBnyVbion8gVV0vJ83-VyfDBE#
Nerem RM, Sambanis A. Tissue engineering: From biology to biological substitutes. Tissue Eng. 1995 [citado 2010 ene 15];1(1). Disponible en: http://www.liebertonline.com/doi/abs/10.1089/ten.1995.1.3
Minami Y, Sigihara H, Oono S. Reconstruction of cornea in three-dimensional collagen gel matrix culture. Invest Ophthalmol Vis Sci. 1993 [citado 2010 ene 15];34(7). Disponible en: http://www.iovs.org/content/34/7/2316.short
Orwin EJ, Hubel A. In Vitro culture characteristics of corneal epithelial, endotelial and keratocyte cells in a native collagen matrix. Tissue Eng. 2000 [citado 2010 ene 15];6(4). Disponible en: http://www.liebertonline.com/doi/abs/10.1089/107632700418038
Reichl S, Müller-Goymann CC. The use of a porcine organotypic cornea construct for permeation studies from formulations containing befunolol hydrochloride. Int J Pharm. 2003 [citado 2010 ene 15];250(1). Disponible en: http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T7W-478RNXS-2&_user=10&_coverDate=01%2F02%2F2003&_rdoc=1&_fmt=high&_orig=gateway&_origin=gateway&_sort=d&_docanchor=&view=c&_searchStrId=1698441877&_rerunOrigin=google&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=9fb97165324572fc4446be64b1c968d3&searchtype=a
Schneider AI, Maier-Reif K, Graeve T. Constructing an in Vitro cornea from cultures of the three specific corneal cell types. In Vitro Cell Dev Biol Anim. 1999 [citado 2010 ene 15];35(9). Disponible en: http://www.springerlink.com/content/b150005vj8823v31/
Zieske JD, Mason VS, Wasson ME, Meunier SF, Nolte CJ, Fukai N, et al. Basement membrane assembly and differentiation of cultures corneal cells: importance of culture enviroment and endothelial cell interaction. Exp Cell Res. 1994 [citado 2010 ene 15];214(2). Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/7523155
Duan D, Klenkler BJ, Sheardown H. Progress in the development of a corneal replacemente: keratoprotheses and tissue-engineered corneas. Expert Rev Med Devices. 2006 [citado 2010 ene 15];3(1). Disponible en: http://www.ingentaconnect.com/content/ftd/erd/2006/00000003/00000001/art00009
Borene ML, Barocas VH, Hubel A. Mechanical and cellular changes during compaction of a collagen-sponge-based corneal stromal equivalent. Ann Biomed Eng. 2004 [citado 2010 ene 15];32(2). Disponible en: http://www.springerlink.com/content/x53057nh135u915h/
Ousley PJ, Terry MA. Objetive screening methods for prior refractive surgery in donor tissue. Cornea. 2002 [citado 2010 ene 15];21(2). Disponible en: http://journals.lww.com/corneajrnl/Abstract/2002/03000/Objective_Screening_Methods_for_Prior_Refractive.11.aspx
Coster DJ, Willians KA. The impact of corneal allograf rejection on the long-term outcome of corneal transplantation. Am J Ophthalmol. 2005 [citado 2010 ene 15];140(6). Disponible en: http://www.ajo.com/article/S0002-9394(05)00795-6/abstract
Caron MJ, Wison R. Review of the risk of HIV infection through corneal transplantation in the United States. J Am Optom Assoc. 1994 [citado 2010 ene 15];65(3). Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/8201168
Hoft RH, Pflugfelder SC, Foster RK, Ullman S, Polack FM, Schiff ER. Clinical evidence for hepatitis B transmisión resulting from corneal transplantation. Cornea. 1997 [citado 2010 ene 15];16(2). Disponible en: http://journals.lww.com/corneajrnl/Abstract/1997/03000/Clinical_Evidence_for_Hepatitis_B_Transmission.3.aspx
Houff SA, Burton RC, Wilson RW, Henson TE, London WT, Baer GM, et al. Human-to-human transmission of rabies virus by corneal transplant. N Engl J Med. 1979 [citado 2010 ene 15];300(11). Disponible en: http://www.nejm.org/doi/pdf/10.1056/NEJM197903153001105
Robert PY, Adenis JP, Pleyer U. How "safe" is corneal transplantation? A contribution on the risk of HSV-transmission due to corneal transplantation. Klin Monatsbl Augenheilkd. 2005 [citado 2010 ene 15];222(11). Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/16308818
Herrera L, Martínez C, Carrasco H, Hansen AM, Urdaneta-Morales S, et al. Cornea as a tissue reservoir of Tripanosoma cruzi. Parasitol Res. 2007 [citado 2010 ene 15];100(6). Disponible en: http://www.springerlink.com/content/g6820812643wl15q/
Hassan SS, Wilhelmus KR, Dahl P, Davis GC, Roberts RT,Ross KW, et al. Infectious disease risk factors of corneal graft donors. Arch Ophthalmol. 2008 [citado 2010 ene 15];126(2). Disponible en: http://archopht.ama-assn.org/cgi/content/abstract/126/2/235
Schotveld JH, Raijmakers AJ, Ype H, Zaal MJ. Donor-to-host transmitted Candida endophthalmitis after penetrating keratoplasty. Cornea. 2005 [citado 2010 ene 15];24(7). Disponible en: http://journals.lww.com/corneajrnl/Abstract/2005/10000/Donor_to_Host_Transmitted_Candida_Endophthalmitis.26.aspx
Borderie VM, Sabolic V, Touzeau O, Scheer S, Carvajal-Gonzalez S, Laroche L. Screening human donor corneas during organ culture for the presence of guttae. Br J Ophthalmol. 2001 [citado 2010 ene 15];85(3). Disponible en: http://bjo.bmj.com/content/85/3/272.abstract
McGeorge AJ, Vote BJ, Elliot DA. Papillary adenocarcinoma of the iris transmited by corneal transplantation. Arch Ophthalmol. 2002 [citado 2010 ene 15];120(10). Disponible en: http://archopht.ama-assn.org/cgi/content/full/120/10/1379
Harrison DA, Hodge DO, Bourne WN. Outcome of corneal grafting with donor tissue from eyes with primary choroidal melanomas. A retrospective cohort comparison. Arch Ophthalmol. 1995 [citado 2010 ene 15];113(6). Disponible en: http://archopht.ama-assn.org/cgi/content/abstract/113/6/753
Salame N, Viel JF, Arveux P, Bernard D. Cancer transmission through corneal transplantation. Cornea. 2001 [citado 2010 ene 15];20(7). Disponible en: http://journals.lww.com/corneajrnl/Abstract/2001/10000/Cancer_Transmission_Through_Corneal.2.aspx
Reichl S, Bednarz J, Müller-Goymann CC. Human corneal equivalents as cell culture model for in Vitro drug permeation studies. Br J Ophthalmol. 2004 [citado 2010 ene 15];88(4). Disponible en: http://bjo.bmj.com/content/88/4/560.abstract
Tegtmeyer S, Papantoniou I, Müller-Goymann CC. Reconstruction o fan in Vitro cornea and its use for grugs permeation studies from different formulations containing pilocarpine hydrochloride. Eur J Pharm Biopharm. 2001 [citado 2010 ene 15];51(2). Disponible en: http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T6C-42D82H0-3&_user=10&_coverDate=03%2F31%2F2001&_rdoc=1&_fmt=high&_orig=gateway&_origin=gateway&_sort=d&_docanchor=&view=c&_searchStrId=1698459519&_rerunOrigin=scholar.google&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=3ece11717ba680bc7b236ba65d45f6d5&searchtype=a
Joyce NC. Proliferative capacity of the corneal endothelium. Progr Retin Eyes Res. 2003 [citado 2010 ene 15];22(3). Disponible en: http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TBT-4840MKY-7&_user=10&_coverDate=05%2F31%2F2003&_rdoc=1&_fmt=high&_orig=gateway&_origin=gateway&_sort=d&_docanchor=&view=c&_searchStrId=1698462316&_rerunOrigin=scholar.google&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=7978e052e3a5a3dea448677e15c230c5&searchtype=a
Sumide T, Nishida K, Yamato M, Takeshi I, Hayashida Y, Watanabe K, et al. Functional human corneal endotelial cell sheets harvested from temperature-responsive culture surfaces. FASEB J. 2006 [citado 2010 ene 15];20(2). Disponible en: http://www.fasebj.org/content/20/2/392.full.pdf
Gascón Ginel MI. Desarrollo del sistema de cohesión intercelular en el epitelio corneal humano generado por ingeniería tisular. Estudio genético o histológico [Tesis]. Granada: Facultad de Medicina, Universidad de Granada; 2008 [citado 2010 ene 15]. Disponible en: http://hdl.handle.net/10481/1890