2012, Number 2
Association between variables severity scales and complications in acute pancreatitis
Sánchez VL, Garrido LR, Castellanos CL, Jiménez SNG, Melchor LA, Guerrero GJ
Language: Spanish
References: 11
Page: 97-102
PDF size: 277.76 Kb.
ABSTRACT
Background: The close monitoring of patients with acute pancreatitis, has led to reduction in mortality able to detect and treat complications as soon as possible. 20-30% develops severe symptoms associated with them. Various scales have been developed to asses risk of complications but a disadvantage is the availability of elements to evaluate and practicality.Objective: to determine the variables most useful because of their association predicts the presence of complications in acute pancreatitis and suggest a scale of evaluation.
Material and methods: We studied 73 patients, 43 were excluded and entering 30. Sample calculation is performed, OR, significance (t.student) and correlation (Pearson). Creating a scale by measuring sensitivity, specificity, PPV and NPV. CI 95%. P≤0.05
Results: OR (CI 95%): HCTO-SRIS: 1.78, HCTO-Death: 1.19, PLT-Necrosis: 1.45, PLT- SRIS: 2.90, DB-Necrosis: 1.52, lactato-necrosis: 7.5, lactato-SIRS: 10.2. Difference: necrosis-lactato (p=0.012), SRIS-HCTO y lactato (p=0.013, p=0.0001), Death-Urea, HCTO, HCO3 y lactato (p=0.008, p=0.048, p=0.014, p=0 .000). Correlación: PLT-Death (p= 0.031), Urea-Death (p=0.035), Leucocitosis-Death (p=0.022), pCO2-Death (p=0.002) y lactato-necrosis, SRIS-Death (p=0.005, p=0.0001 y p=0.002).
Conclusions: The most significant variables predicted creats a scale DISEP having a sensitivity of 90% and specificity of 80% with PPV of 69% and NVP of 94%. Taking court in › 7 points. Obtaining a practical scale for your application predicts. Applicable at any time in the first 48 hours and with element that are sustainable in a hospital
REFERENCES