medigraphic.com
ISSN 1561-3054 (Electronic)

2012, Number 1

<< Back

Rev Cubana Med Trop 2012; 64 (1)

First report of infective endocarditis in Cuba as a result of brucellosis

García GGS, Saborido PIM, Ramírez LL, Ponce de León ÁI

Language: Spanish
References: 15
Page: 65-68
PDF size: 82.79 Kb.


ABSTRACT

Introduction: the clinical manifestations of brucellosis have been poorly researched on and the symptoms and possible complications have not been deeply studied either. Objective: to report a case of infective endocarditis caused by brucellosis for the first time in Cuba. Methods: a Caucasian male farmer aged 57 years was referred from Vertientes municipality to be admitted at “Manuel Ascunce Domenech” provincial hospital in Camaguey province in December,2009. He had been presumptively diagnosed with infectious endocarditis caused by Brucella and with moderate aortic failure since he presented with fever, general malaise, fatigue, muscle and joint pains, arthritis, marked asthenia, anorexia, neurological signs, sweating and strong chest pain. In his previous hospitalization, he had been treated with antimicrobials after indication of supplementary tests such as slow serology for brucellosis; however, specific reagents were not available,so these tests were not performed until January 2010.The epidemiological history of this case included his direct contact with cows and pigs as well as wounds and minor traumas inflicted on his hands and feet resulting from his type of work. His farm is next to another farm where the cattle is also affected with brucellosis. Results: the lab tests were positive with high serological titres, and although it was not possible to isolate the etiologic agent through culturing, the disease and the infective endocarditis were serologically confirmed as additional complication; this required antimicrobial treatment and drugs for the heart disease. These complications from brucellosis are barely diagnosed in the international literature, and in Cuba, this is the first report of the disease. Conclusions: the description of this case is an alert to diagnosis of infective endocarditis that may be associated with epidemiological history of brucellosis.


REFERENCES

  1. Young E. An overview of human brucellosis. Clin Infect Dis. 1995;21:283-90.

  2. Segura JC. Guías Clínicas [serie en internet]. 2005 [citado 20 Ago 2010];5(24). Disponible en: http://www.fisterra.com/ guias2/brucelosis.asp

  3. Acha PN, Szyfries B. Zoonosis y enfermedades transmisibles comunes al hombre y los animales. Bacteriosis y micosis. Vol, 2. 3ra ed. Washington, D.C.: OPS-OMS; 2001. p. 28-52. (Publicación científica y técnica No. 580)

  4. Figueroa-Arredondo P, Luna AL. Zoonosis. Listeria, Francisella, Brucella, bacilos y Yersinia. En: Microbiología e Inmunología [serie en internet]; 2005 citado 20 Ago 2010]. Disponible en: http:///F|/Actualizaciones%20Mundiales/4%20 septiembre/chapter17.htm

  5. Castro HA, González SR, Prat MI. Brucelosis: una revisión práctica. Acta Bioquim Clin Latinoam. 2005;39(2):203-16.

  6. Situación Epidemiológica Internacional. Vigilancia en Salud [serie en internet]. 2010 [citado 20 Ago 2010]. Disponible en: http://files.sld.cu/vigilancia/files/2010/08/sei300710.pdf

  7. Morales DF, Combariza DA. Seoprevalencia de brucelosis en trabajadores de matadero de municipios del Tolima, Colombia. Rev Cienc Salud. 2004;2(1):15-23.

  8. Cruz R, Gandul L, Oliver M, Machado O, Rodríguez C, Seoane G, et al. Programa Nacional de Prevención y Control de la Brucelosis Humana. La Habana: Editorial Seruinpres; 1998. p. 40.

  9. Olea M Pilar. Endocarditis por Brucella abortus: Sobrevivir a los 74 años de edad. Rev Chil Infectol. 2010;27(1):80-4.

  10. Soloaga R, Salinas A, Poterallo M, Margari A, Suar B, Lucero N, et al. Bacteriemia por Brucella canis: Aislamiento con el Sistema Bact-Alert. Rev Argent Microbiol. 2004;36(2):81-4.

  11. Rubio V, Hernández JR, Dorronsoro I, Marrodan C, Díaz G. Diagnóstico de la brucelosis humana. Influencia del pH en la prueba de seroaglutinacion y sobre la actividad aglutinante de los anticuerpos IgM, IgG e IgA. Enferm Infecc Microbiol Clin. 2002;20(4):144-9.

  12. Poveda J, Soriano T, Canas A, Rodríguez L. Diagnóstico y manejo de la endocarditis infecciosa. Rev Costarric Cardiol[serie en internet]. 2003 [citado 20 Ago 2010];5(2). Disponible en: http://www.scielo.sa.cr/scielo.php?script=sciarttext&pid=S1409-41422003000200 00 2&lng=es&nrm=iso. ISSN 1409-4142.

  13. Purwar S, Metgud SC, Darshan A, Mutnal MB, Nagmoti MB. Infective endocarditis due to brucella. Indian J Med Microbiol. 2006;24:286-8.

  14. Simarro E, Pérez J, Ruiz J, Gómez J. Fallo en la detección de Brucella melitensis en tres sistemas de hemocultivo. Enferm Infecc Microbiol Clin. 2001;19(1):35-6.

  15. Rodríguez A, Domínguez Ma, Sánchez A. Endocarditis infecciosa. En: Fajardo J, editor. Principios de urgencia, emergencia y cuidados críticos [serie en internet]; 2009 [citado 20 Ago 2010]. Disponible en: http://tratado.uninet.edu/c010710.html




2020     |     www.medigraphic.com